Medication-overuse headache (MOH) is defined by the International Classification of
Headache Disorders as a headache in patients with a pre-existing primary headache …

Medication overuse in primary headache disorders is a worldwide phenomenon and has a
role in the chronification of headache disorders. The burden of disease on individuals and …

Quantitative sensory testing (QST) is widely used to assess somatosensory function by
application of controlled stimuli across a variety of modalities. The aim of the present meta …

Background The majority of individuals with post-traumatic headache have symptoms that
are indistinguishable from migraine. The overlap in symptoms amongst these individuals …

Neuroimaging studies are beginning to shed light on the mechanisms underlying the
development and evolution of migraine and its specific symptoms. Future studies have the …

Migraine—a disabling neurological disorder, imposes a tremendous burden on societies. To
reduce the economic and health toll of the disease, insight into its pathophysiological …

Background and aim A recent sham-controlled trial showed that external trigeminal nerve
stimulation (eTNS) is effective in episodic migraine (MO) prevention. However, its …

We explored the functional pattern of the pain-processing network in patients with migraine,
in the interictal periods, during trigeminal noxious stimulation. Contact heat evoked potential …

Background Research imaging of brain structure and function has helped to elucidate the
pathophysiology of medication overuse headache (MOH). Methods This is a narrative …

Background Several previous studies have investigated cortical abnormalities, specifically
cortical thickness, in patients with migraine, with variable results. The relatively small sample …