Bone, as a mineralized composite of inorganic (mostly carbonated hydroxyapatite) and
organic (mainly type I collagen) phases, possesses a unique combination of remarkable …

Hydroxyapatite (HA) reinforced collagen fibrils serve as the basic building blocks of natural
bone and dentin. Mineralization of collagen fibrils play an essential role in ensuring the …

INTRODUCTION The components of bone assemble hierarchically to provide stiffness and
toughness. Deciphering the specific organization and relationship between bone's principal …

In this review, most of the known and postulated mechanisms of osteopontin (OPN) and its
role in bone remodeling and orthodontic tooth movement are discussed based on available …

Engineering biomaterials that mimic the extracellular matrix (ECM) of bone is of significant
importance since most of the outstanding properties of the bone are due to matrix …

Bone tissue, by definition, is an organic–inorganic nanocomposite, where metabolically
active cells are embedded within a matrix that is heavily calcified on the nanoscale …

The effects of strength training (ST) on the mechanical bone strength and osteogenic
differentiation of bone marrow mesenchymal stromal cells (BMSCs) from adult, aged and …

Osteopontin (OPN) is a non-collagenous protein involved in biomineralization of bone
tissue. Beyond its role in biomineralization, we show that osteopontin is essential to the …

Synthetic substitutes of bone grafts, such as calcium phosphate–based ceramics, have
shown some good clinical successes in the regeneration of large bone defects and are …

Dental clinicians have relied for centuries on traditional dental materials (polymers,
ceramics, metals, and composites) to restore oral health and function to patients. Clinical …