Red blood cells (RBCs) are a specialised organ that enabled the evolution of multicellular
organisms by supplying a sufficient quantity of oxygen to cells that cannot obtain oxygen …

Red blood cells (RBC) are the most abundant cell in the human body, with a central role in
oxygen transport and its delivery to tissues. However, omics technologies recently revealed …

The SARS-CoV-2 beta coronavirus is the etiological driver of COVID-19 disease, which is
primarily characterized by shortness of breath, persistent dry cough, and fever. Because they …

Transfusion of red blood cells (RBCs) is one of the most valuable and widespread
treatments in modern medicine. Lifesaving RBC transfusions are facilitated by the cold …

Background Endothelial cell (EC) injury accelerates the progression of diabetic
macrovascular complications. Hypoxia is an important cause of EC injury. Hypoxia-inducible …

Red blood cell (RBC) storage in the blood bank promotes the progressive accumulation of
metabolic alterations that may ultimately impact the erythrocyte capacity to cope with oxidant …

Mature red blood cells (RBCs) lack mitochondria and thus exclusively rely on glycolysis to
generate adenosine triphosphate (ATP) during aging in vivo or storage in blood banks …

Red blood cell transfusion is a life-saving intervention, and storage is a logistic necessity to
make~ 110 million units available for transfusion every year worldwide. However, storage in …

BACKGROUND Glucose-6-phosphate dehydrogenase (G6PD) deficiency decreases the
ability of red blood cells (RBCs) to withstand oxidative stress. Refrigerated storage of RBCs …

Sickle cell disease (SCD) is an inherited blood disorder characterized by sickled red blood
cells (RBCs), which are more sensitive to haemolysis and can contribute to disease …