Pharma [e] cology: how the gut microbiome contributes to variations in drug response

KR Trepka, CA Olson, V Upadhyay… - Annual Review of …, 2024 - annualreviews.org
Drugs represent our first, and sometimes last, line of defense for many diseases, yet despite
decades of research we still do not fully understand why a given drug works in one patient …

[HTML][HTML] A diet-dependent host metabolite shapes the gut microbiota to protect from autoimmunity

M Alexander, V Upadhyay, R Rock, L Ramirez… - Cell reports, 2024 - cell.com
Diet can protect from autoimmune disease; however, whether diet acts via the host and/or
microbiome remains unclear. Here, we use a ketogenic diet (KD) as a model to dissect these …

Risk factors and clinical outcomes associated with multiple as opposed to single pathogens detected on the gastrointestinal disease polymerase chain reaction assay

I Mannstadt, AM Choy, J Li, DA Green, DE Freedberg - Gut Pathogens, 2024 - Springer
Background The use of gastrointestinal disease multiplex polymerase chain reaction (GI
PCR) testing has become common for suspected gastrointestinal infection. Patients often …