microRNAs in action: biogenesis, function and regulation
Ever since microRNAs (miRNAs) were first recognized as an extensive gene family> 20
years ago, a broad community of researchers was drawn to investigate the universe of small …
years ago, a broad community of researchers was drawn to investigate the universe of small …
Functional mechanism and clinical implications of MicroRNA‐423 in human cancers
RS Ke, LZ Lv, SY Zhang, FX Zhang, Y Jiang - Cancer medicine, 2020 - Wiley Online Library
MicroRNAs play a vital role in the regulatory mechanisms of tumorigenesis. Current
research indicates that microRNA‐423 (miR‐423) is abnormally expressed in various …
research indicates that microRNA‐423 (miR‐423) is abnormally expressed in various …
The Enrichment of miRNA-Targeted mRNAs in Translationally Less Active over More Active Polysomes
Simple Summary MicroRNAs (miRNA) inhibit the translation and enhance the degradation
of their target mRNAs, but only moderately. Paradoxically, miRNAs and their target mRNAs …
of their target mRNAs, but only moderately. Paradoxically, miRNAs and their target mRNAs …
Comparative analysis of microRNA binding site distribution and microRNA-mediated gene expression repression of oncogenes and tumor suppressor genes
MicroRNAs (miRNAs) are a family of short, noncoding RNAs that can regulate gene
expression levels of over half of the human genome. Previous studies on the role of miRNAs …
expression levels of over half of the human genome. Previous studies on the role of miRNAs …
Double-Stranded RNA Targeting White Mold Sclerotinia sclerotiorum Argonaute 2 for Disease Control via Spray-Induced Gene Silencing
S Mukherjee, G Beligala, C Feng… - Phytopathology …, 2024 - Am Phytopath Society
Sclerotinia sclerotiorum, the causal agent of white mold infection, is a cosmopolitan fungal
pathogen that causes major yield losses in many economically important crops. Spray …
pathogen that causes major yield losses in many economically important crops. Spray …
Tumor evolution selectively inactivates the core microRNA machinery for immune evasion
Cancer cells acquire genetic heterogeneity to escape from immune surveillance during
tumor evolution, but a systematic approach to distinguish driver from passenger mutations is …
tumor evolution, but a systematic approach to distinguish driver from passenger mutations is …
[HTML][HTML] Non-Linear Relationship between MiRNA Regulatory Activity and Binding Site Counts on Target mRNAs
MicroRNAs (miRNA) exert regulatory actions via base pairing with their binding sites on
target mRNAs. Cooperative binding, ie, synergism, among binding sites on an mRNA is …
target mRNAs. Cooperative binding, ie, synergism, among binding sites on an mRNA is …
Nucleic acid strategies for infectious disease treatments: The nanoparticle-based oral delivery route
Therapies based on orally administrated nucleic acids have significant potential for the
treatment of infectious diseases, including chronic inflammatory diseases such as …
treatment of infectious diseases, including chronic inflammatory diseases such as …
The Roles of MicroRNA in Gene Expression Regulation and Disease in Human
S Tian - 2024 - ttu-ir.tdl.org
This dissertation investigates the global role of microRNAs (miRNAs) in regulating cancer
genes, focusing on their two major regulatory mechanisms: mRNA destabilization and …
genes, focusing on their two major regulatory mechanisms: mRNA destabilization and …
Double-stranded RNA targeting white mold Sclerotinia sclerotiorum argonaute 2 for disease control via spray-induced gene silencing
SYL Marzano, G Beligala, S Mukherjee, C Feng - 2023 - researchsquare.com
Sclerotinia sclerotiorum, causal agent of white mold infection, is a cosmopolitan fungal
pathogen that causes major yield losses in many economically important crops. Spray …
pathogen that causes major yield losses in many economically important crops. Spray …