International consensus statement on allergy and rhinology: allergic rhinitis

SK Wise, SY Lin, E Toskala, RR Orlandi… - International forum of …, 2018 - Wiley Online Library
Background Critical examination of the quality and validity of available allergic rhinitis (AR)
literature is necessary to improve understanding and to appropriately translate this …

Cysteinyl leukotrienes and their receptors: molecular and functional characteristics

RK Singh, S Gupta, S Dastidar, A Ray - Pharmacology, 2010 - karger.com
The cysteinyl leukotrienes (CysLTs) are a family of potent inflammatory lipid mediators
synthesized from arachidonic acid by a variety of cells including mast cells, eosinophils …

What is asthma? Pathophysiology, demographics, and health care costs

J Maslan, JW Mims - Otolaryngologic Clinics of North America, 2014 - oto.theclinics.com
Asthma is a chronic inflammatory disorder characterized by airway obstruction and
hyperresponsiveness. The medical term “asthma,” which derives from the Greek for …

[HTML][HTML] Acute and chronic rhinosinusitis and allergic rhinitis in relation to comorbidity, ethnicity and environment

R Hoffmans, A Wagemakers, C van Drunen, P Hellings… - PloS one, 2018 - journals.plos.org
Background This study was conducted to assess the effect of comorbidity, ethnicity,
occupation, smoking and place of residence on allergic rhinitis (AR), acute rhinosinusitis …

A review on leukotrienes and their receptors with reference to asthma

RK Singh, R Tandon, SG Dastidar, A Ray - Journal of Asthma, 2013 - Taylor & Francis
Abstract Objective and methods: Leukotrienes (LTs) including cysteinyl leukotrienes
(CysLTs) and LTB4 are the most potent inflammatory lipid mediators and play a central role …

Anti-IgE and anti-IL5 biologic therapy in the treatment of nasal polyposis: a systematic review and meta-analysis

A Rivero, J Liang - Annals of Otology, Rhinology & …, 2017 - journals.sagepub.com
Objective: To determine the role of biologic therapy on sinonasal symptoms and objective
outcomes in chronic rhinosinusitis with nasal polyposis (CRSwNP). Methods: PubMed, OVID …

Atopic profile of patients failing medical therapy for chronic rhinosinusitis

BK Tan, W Zirkle, RK Chandra, D Lin… - International forum of …, 2011 - Wiley Online Library
Background Chronic rhinosinusitis (CRS) is an inflammatory condition of the nasal airway
and paranasal sinuses that can broadly be classified into CRS with nasal polyps (CRSwNP) …

Management of the upper airway in cystic fibrosis

EA Illing, BA Woodworth - Current opinion in pulmonary medicine, 2014 - journals.lww.com
Well designed clinical trials with long-term follow-up concerning medical and surgical
interventions for cystic fibrosis sinus disease are required to establish standardized …

Periostin as a biomarker for nasal polyps in chronic rhinosinusitis

AZ Maxfield, LD Landegger, CD Brook… - … –Head and Neck …, 2018 - journals.sagepub.com
Objective Periostin is an extracellular matrix protein that is elevated in the sinonasal tissues
of patients with chronic rhinosinusitis (CRS). The purpose of this study was to determine …

A review of upper airway physiology relevant to the delivery and deposition of inhalation aerosols

T Mekonnen, X Cai, C Burchell, H Gholizadeh… - Advanced Drug Delivery …, 2022 - Elsevier
Developing effective oral inhaled drug delivery treatment strategies for respiratory diseases
necessitates a thorough knowledge of the respiratory system physiology, such as the …