Autologous chimeric antigen receptor (CAR) T cells have changed the therapeutic
landscape in haematological malignancies. Nevertheless, the use of allogeneic CAR T cells …

Chimeric antigen receptor T-cell (CAR-T) therapy has been prosperous in the treatment of
patients with various types of relapsed/refractory (R/R) B-cell malignancies including diffuse …

Background Bisphosphonates have profound effects on bone physiology, and could modify
the process of metastasis. We undertook collaborative meta-analyses to clarify the risks and …

This review describes the key discoveries over the last 15 years that have led to a clearer
understanding of the molecular mechanisms by which bisphosphonate drugs inhibit bone …

Bisphosphonates (BP) are a class of calcium-binding drug used to prevent bone resorption
in skeletal disorders such as osteoporosis and metastatic bone disease. They act by …

γδ T cells have recently gained considerable attention as an attractive tool for cancer
adoptive immunotherapy due to their potent anti-tumor activity and unique role in …

Chimeric antigen receptor T-cells (CAR-Ts) are known as revolutionary living drugs that
have turned the tables of conventional cancer treatments in certain hematologic …

Tumour cells migrate very early from primary sites to distant sites, and yet metastases often
take years to manifest themselves clinically or never even surface within a patient's lifetime …

γδ T cells hold promise for adoptive immunotherapy because of their reactivity to bacteria,
viruses, and tumors. However, these cells represent a small fraction (1–5%) of the peripheral …

Osteonecrosis of the jaw (ONJ) is an uncommon condition noted to occur in patients who are
receiving osteoclast-targeted antiresorptive therapy. The incidence of ONJ in patients taking …