Choroid plexus and the blood–cerebrospinal fluid barrier in disease

P Solár, A Zamani, L Kubíčková, P Dubový… - Fluids and Barriers of the …, 2020 - Springer
The choroid plexus (CP) forming the blood–cerebrospinal fluid (B-CSF) barrier is among the
least studied structures of the central nervous system (CNS) despite its clinical importance …

Neurological manifestations in dogs naturally infected by Leishmania infantum: descriptions of 10 cases and a review of the literature

AP Giannuzzi, M Ricciardi… - Journal of Small …, 2017 - Wiley Online Library
In order to evaluate possible nervous system involvement in canine leishmaniasis,
retrospective evaluation of all medical records of leishmaniotic dogs exhibiting neurological …

Occurrence of Leishmania infantum in the central nervous system of naturally infected dogs: Parasite load, viability, co-infections and histological alterations

VC Oliveira, VC Boechat, AAV Mendes Junior… - PloS one, 2017 - journals.plos.org
Zoonotic visceral leishmaniasis is caused by the protozoan Leishmania infantum and little is
known about the occurrence and pathogenesis of this parasite in the CNS. The aims of this …

Lymphocytic hypophysitis in dogs infected with Leishmania spp.

ED Frigerio, CC Guizelini, GG Jussiani… - Frontiers in Veterinary …, 2023 - frontiersin.org
Background Morphological involvement of endocrine glands, such as the pituitary gland,
remain uninvestigated in dogs with canine visceral leishmaniasis. Therefore, this study …

Neurological disease in human and canine leishmaniasis–clinical features and immunopathogenesis

CSF Maia, MC Monteiro, EC Gavioli… - Parasite …, 2015 - Wiley Online Library
Leishmaniasis is a vectorborne disease caused by Leishmania protozoa, which is a major
health problem and a neglected disease common in many regions of the world. Leishmania …

Unveiling Cerebral Leishmaniasis: parasites and brain inflammation in Leishmania donovani infected mice

GD Melo, S Goyard, L Fiette, A Boissonnas… - Scientific reports, 2017 - nature.com
Visceral leishmaniasis (VL) is a systemic disease with multifaceted clinical manifestations,
including neurological signs, however, the involvement of the nervous system during VL is …

Levels of matrix metalloproteinase‐2 and metalloproteinase‐9 in the cerebrospinal fluid of dogs with visceral leishmaniasis

NR Marangoni, GD Melo, OC Moraes… - Parasite …, 2011 - Wiley Online Library
Inflammation causes increases in the level of matrix metalloproteinases (MMPs), which, in
central nervous system (CNS), are associated with neuroinflammation and disruption of …

[HTML][HTML] Pro-inflammatory cytokines predominate in the brains of dogs with visceral leishmaniasis: a natural model of neuroinflammation during systemic parasitic …

GD Melo, TF Seraguci, A Schweigert, JES Silva… - Veterinary …, 2013 - Elsevier
Visceral leishmaniasis is a multisystemic zoonotic disease that can manifest with several
symptoms, including neurological disorders. To investigate the pathogenesis of brain …

Leishmania infection and neuroinflammation: Specific chemokine profile and absence of parasites in the brain of naturally-infected dogs

GD Melo, JES Silva, FG Grano, MS Souza… - Journal of …, 2015 - Elsevier
Visceral leishmaniasis is a chronic disease caused by Leishmania infantum. We aimed to
detect the parasite in the brain of fifteen naturally-infected dogs using in situ hybridization …

Differential alterations in the activity of matrix metalloproteinases within the nervous tissue of dogs in distinct manifestations of visceral leishmaniasis

GF Machado, GD Melo, OC Moraes, MS Souza… - Veterinary immunology …, 2010 - Elsevier
Canine visceral leishmaniasis is an important emerging disease with a multitude of clinical
symptoms, including neurological alterations. Matrix metalloproteinases (MMP) are …