Autophagy is a self-eating cellular catabolic pathway, through which long-lived proteins,
damaged organelles and misfolded proteins are degraded and recycled for the …

Melatonin, more commonly known as the sleep hormone, is mainly secreted by the pineal
gland in dark conditions and regulates the circadian rhythm of the organism. Its intrinsic …

We previously demonstrated that multipotent mesenchymal stromal cells (MSCs) that
overexpress microRNA 133b (miR-133b) significantly improve functional recovery in rats …

Perinatal insults such as hypoxia–ischemia induces secondary brain injury. In order to
develop the next generation of neuroprotective therapies, we urgently need to understand …

Emerging evidence indicates that heat shock proteins (HSPs) are critical regulators in
normal neural physiological function as well as in cell stress responses. The functions of …

Evidence suggests that autophagy may be a new therapeutic target for stroke, but whether
activation of autophagy increases or decreases the rate of neuronal death is still under …

Several recent studies have showed that autophagy is involved in ischemic brain damage,
but it may also play a pro-survival role in ischemic preconditioning. This study was taken to …

Autophagy is a catalytic process of the bulk degradation of long‐lived cellular components,
ultimately resulting in lysosomal digestion within mature cytoplasmic compartments known …

Abstract Sirtuin3 (Sirt3) is a member of the silent information regulator 2 (Sir2) family of
proteins located in mitochondria that influences almost every major aspect of mitochondrial …

Ischemic stroke refers to brain tissue ischemia, hypoxic necrosis, and brain softening caused
by the interruption of the blood supply to the brain without adequate collateral circulation …