Background Comprehensive literature reviews of historical perspectives and evidence
supporting cannabis/cannabinoids in the treatment of pain, including migraine and …

Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …

Cannabis has been used for centuries to treat seizures. Recent anecdotal reports,
accumulating animal model data, and mechanistic insights have raised interest in cannabis …

Background The use of cannabis, or marijuana, for medicinal purposes is deeply rooted
though history, dating back to ancient times. It once held a prominent position in the history …

Simple Summary Our understanding of the Endocannabinoid System of animals, and its
ubiquitous presence in nearly all members of Animalia, has opened the door to novel …

The active compound in herbal cannabis, Δ9‐tetrahydrocannabinol, exerts all of its known
central effects through the CB1 cannabinoid receptor. Research on cannabinoid …

Alzheimer9s disease (AD) is characterized by enhanced β-amyloid peptide (βA) deposition
along with glial activation in senile plaques, selective neuronal loss, and cognitive deficits …

The Cannabis sativa herb contains over 100 phytocannabinoid (pCB) compounds and has
been used for thousands of years for both recreational and medicinal purposes. In the past …

Traumatic brain injury triggers the accumulation of harmful mediators that may lead to
secondary damage,. Protective mechanisms to attenuate damage are also set in motion. 2 …

In the last 25 years data has grown exponentially dealing with the discovery of the
endocannabinoid system consisting of specific cannabinoid receptors, their endogenous …