Vascular flow modelling can improve our understanding of vascular pathologies and aid in
developing safe and effective medical devices. Vascular flow models typically involve …

Determining brain hemodynamics plays a critical role in the diagnosis and treatment of
various cerebrovascular diseases. In this work, we put forth a physics-informed deep …

The advancement of ischaemic stroke treatment relies on resource-intensive experiments
and clinical trials. In order to improve ischaemic stroke treatments, such as thrombolysis and …

In this review, we provide a summary of the state-of-the-art in the in silico modelling of
cerebral blood flow (CBF) and its application in in silico clinical trials. CBF plays a key role in …

Cerebral perfusion modelling is a promising tool to predict the impact of acute ischaemic
stroke treatments on the spatial distribution of cerebral blood flow (CBF) in the human brain …

Abstract Models of the micro-circulatory blood flow in the brain can play a key role in
understanding the variety of cerebrovascular diseases that occur in the microvasculature …

An in silico trial simulates a disease and its corresponding therapies on a cohort of virtual
patients to support the development and evaluation of medical devices, drugs, and …

The dynamics of blood flow in the smallest vessels and passages of the human body, where
the cellular character of blood becomes prominent, plays a dominant role in the transport …

Computational physiological models are promising tools to enhance the design of clinical
trials and to assist in decision making. Organ-scale haemodynamic models are gaining …

Early diagnosis of kidney disease remains an unmet clinical challenge, preventing timely
and effective intervention. Diabetes and hypertension are two main causes of kidney …