Tuft cells are rare, secretory epithelial cells that generated scant immunological interest until
contemporaneous reports in 2016 linked tuft cells with type 2 immunity in the small intestine …

Tuft cells—rare solitary chemosensory cells in mucosal epithelia—are undergoing intense
scientific scrutiny fueled by recent discovery of unsuspected connections to type 2 immunity …

Since the worldwide spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) infection, management of coronavirus disease 2019 (COVID-19) has been challenging for …

Tuft cells are found in tissues with distinct stem cell compartments, tissue architecture, and
luminal exposures but converge on a shared transcriptional program, including expression …

Peripheral taste receptor cells use multiple signaling pathways to transduce taste stimuli into
output signals that are sent to the brain. Transient receptor potential melastatin 5 (TRPM5), a …

As a result of the COVID-19 pandemic, evidence revealed that SARS-CoV-2 infection
caused taste loss at a rate higher than that of influenza. ACE2, the entry receptor of SARS …

In the last few years, single-cell profiling of taste cells and ganglion cells has advanced our
understanding of transduction, encoding, and transmission of information from taste buds as …

Rhodopsin is a light receptor comprised of an opsin protein and a light-sensitive retinal
chromophore. Despite more than a century of scrutiny, there is no evidence that opsins …

Abstract “Salty taste” sensation is evoked when sodium and chloride ions are present
together in the oral cavity. The presence of an epithelial cation channel that receives Na+ …

Opsins, the protein moieties of animal visual photo-pigments, have emerged as
moonlighting proteins with diverse, light-dependent and-independent physiological …