Nitric oxide (NO) is an important signaling molecule that is involved in a wide range of
physiological and pathological events in biology. Metal coordination chemistry, especially …

Haemoglobin (Hb) is widely known as the iron-containing protein in blood that is essential
for O 2 transport in mammals. Less widely recognised is that erythrocyte Hb belongs to a …

Nitrite is one of the players in the broad nitrogen biogeochemical cycle. This nitrogen oxo-
anion is involved in key pathways crucial to life on Earth and to the planetary “recycling” of …

The heme iron complex is one of the most important cofactors in biological systems (Figure
1). The major functions of the heme iron complex are to serve as the O2 binding site for …

The availability of genomic information from the three kingdoms of life has altered
substantially our view of the globin superfamily. It is now evident that Hbs, 2 defined as …

The heme prosthetic group in hemoglobins is most often attached to the globin through
coordination of either one or two histidine side chains. Those proteins with one histidine …

Genomics has produced hundreds of new hemoglobin sequences with examples in nearly
every living organism. Structural and biochemical characterizations of many recombinant …

Through nitrosylation of [Fe–S] proteins, or the chelatable iron pool, a dinitrosyl iron unit
(DNIU)[Fe (NO) 2] embedded in the form of low-molecular-weight/protein-bound dinitrosyl …

Nitric oxide (NO) is an inevitable product of life in an oxygen-and nitrogen-rich environment.
This reactive diatomic molecule exhibits microbial cytotoxicity, in large part by facilitating …

The short‐lived hydrophobic gas nitric oxide (NO) is a broadly conserved signaling molecule
in all domains of life, including the ubiquitous and versatile filamentous fungi (molds) …