Multifaceted bioactivity of thiosemicarbazide derivatives: Synthesis, characterization, and DFT investigations on inhibition of α-amylase, hydroxyl radical scavenging …
In this study, eight bioactive thiosemicarbazide derivatives (3a-h) were synthesized and
characterized through 1 HNMR, 13 CNMR and Mass spectroscopic techniques. Finally, their …
characterized through 1 HNMR, 13 CNMR and Mass spectroscopic techniques. Finally, their …
Design, spectral, antibacterial and in-silico studies of new thiosemicarbazones and semicarbazones derived from symmetrical chalcones
N Sharma, N Dhingra, HL Singh - Journal of Molecular Structure, 2024 - Elsevier
A series of new Schiff bases of semicarbazones and thiosemicarbazones have been derived
from the condensation of symmetrical chalcones with semicarbazide and thiosemicarbazide …
from the condensation of symmetrical chalcones with semicarbazide and thiosemicarbazide …
Exploring Juniperus phoenicea L extract through phytochemical analysis, anti-lipase effects, and comprehensive molecular studies
Lipase inhibitors are used in the treatment of candidiasis, obesity, and acne problems.
Therefore, the investigation of new natural lipase inhibitors has generated great interest …
Therefore, the investigation of new natural lipase inhibitors has generated great interest …
Oxidovanadium (V) complexes with chiral tetradentate Schiff bases: Synthesis, spectroscopic characterization, catalytic and biological activity
G Romanowski, J Budka… - Journal of Molecular …, 2024 - Elsevier
New mononuclear oxidovanadium (V) complexes,[(−) VOL 1–10] and [(+) VOL 1–4], with
chiral tetradentate Schiff bases have been obtained by monocondensation of …
chiral tetradentate Schiff bases have been obtained by monocondensation of …
Biaryl carboxamide‐based peptidomimetics analogs as potential pancreatic lipase inhibitors for treating obesity
V Pandey, PA Adhikrao, GM Motiram… - Archiv der …, 2024 - Wiley Online Library
Abstract A series of 1, 1′‐biphenyl‐3‐carboxamide and furan‐phenyl‐carboxamide
analogs were synthesized using an optimized scheme and confirmed by 1H and 13C …
analogs were synthesized using an optimized scheme and confirmed by 1H and 13C …
Integrated insights into the Synthesis and biological significances of novel benzofuran based oxadiazole/thiadiazole derivatives: A comprehensive computational and …
We have synthesized a novel library of benzofuran-derived thiadiazole/oxadiazole-based
thiourea derivatives (1-28) targeting one of the rising health issues all over the world …
thiourea derivatives (1-28) targeting one of the rising health issues all over the world …
Evaluation of antioxidant, antidiabetic and antiobesity potential of phenylpropanoids (PPs): Structure-activity relationship and insight into action mechanisms against …
J Li, CF Qin, ND Chen - Bioorganic Chemistry, 2024 - Elsevier
Phenylpropanoids (PPs), a group of natural compounds characterized by one or more C6-
C3 units, have exhibited considerable potential in addressing metabolic disease. However …
C3 units, have exhibited considerable potential in addressing metabolic disease. However …
Synthesis, characterization, enzyme inhibition and molecular docking studies of benzothiazole derivatives bearing alkyl phenyl ether fragments
Novel benzothiazole derivatives containing alkyl/benzyl phenyl ether fragments have been
synthesized through two step reaction process. Initially, 2-hydroxybenzaldehyde was …
synthesized through two step reaction process. Initially, 2-hydroxybenzaldehyde was …
In silico study of novel coumarin derivatives as potential agents in the pancreatic cancer treatment
S Jeremić, E Avdović, Z Dolićanin… - Computer Methods in …, 2024 - Taylor & Francis
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest diseases. Here are
investigated two synthesized and two hypothetical coumarin derivatives, and their capacity …
investigated two synthesized and two hypothetical coumarin derivatives, and their capacity …
Exploring flavonoid derivatives as potential pancreatic lipase inhibitors for obesity management: An in silico and in vitro study
S Modanwal, AK Maurya, V Mulpuru, N Mishra - Molecular Diversity, 2024 - Springer
Obesity is widely recognized as a major public health issue and is one of the leading causes
of death worldwide. Overweight and obesity are prominent lifestyle ailments that not only …
of death worldwide. Overweight and obesity are prominent lifestyle ailments that not only …