Stem cell-derived exosomes, autophagy, extracellular matrix turnover, and miRNAs in cardiac regeneration during stem cell therapy

P Prathipati, SS Nandi, PK Mishra - Stem Cell Reviews and Reports, 2017 - Springer
Stem cell therapy (SCT) raises the hope for cardiac regeneration in ischemic hearts.
However, underlying molecular mechanisms for repair of dead myocardium by SCT in the …

Noncoding RNAs as regulators of cardiomyocyte proliferation and death

MT Piccoli, SK Gupta, T Thum - Journal of molecular and cellular cardiology, 2015 - Elsevier
Cardiovascular diseases are currently the main cause of morbidity and mortality worldwide.
Ischemic heart disease, in particular, is responsible for the majority of cardiac-related …

[HTML][HTML] A miR-567-PIK3AP1-PI3K/AKT-c-Myc feedback loop regulates tumour growth and chemoresistance in gastric cancer

F Zhang, K Li, X Yao, H Wang, W Li, J Wu, M Li… - …, 2019 - thelancet.com
Background Gastric cancer (GC) ranks the fifth most common cancer, and chemotherapy is
one of the most common treatments for GC. However, chemoresistance limits the …

[HTML][HTML] NGF/TRKA decrease miR-145-5p levels in epithelial ovarian cancer cells

MP Garrido, I Torres, A Avila, J Chnaiderman… - International journal of …, 2020 - mdpi.com
Nerve Growth Factor (NGF) and its high-affinity receptor tropomyosin receptor kinase A
(TRKA) increase their expression during the progression of epithelial ovarian cancer (EOC) …

Signaling pathways and gene regulatory networks in cardiomyocyte differentiation

A Parikh, J Wu, RM Blanton… - Tissue Engineering Part …, 2015 - liebertpub.com
Strategies for harnessing stem cells as a source to treat cell loss in heart disease are the
subject of intense research. Human pluripotent stem cells (hPSCs) can be expanded …

[HTML][HTML] Regulation of cardiac cell fate by microRNAs: implications for heart regeneration

M Gama-Carvalho, J Andrade, L Brás-Rosário - Cells, 2014 - mdpi.com
microRNAs are post-transcriptional regulators of gene expression that have been shown to
be central players in the establishment of cellular programs, often acting as switches that …

MicroRNAs in myocardial ischemia: identifying new targets and tools for treating heart disease. New frontiers for miR-medicine

V Sala, S Bergerone, S Gatti, S Gallo… - Cellular and molecular …, 2014 - Springer
MicroRNAs (miRNAs) are natural, single-stranded, small RNA molecules which subtly
control gene expression. Several studies indicate that specific miRNAs can regulate heart …

MicroRNA-760 inhibits cell viability and migration through down-regulating BST2 in gastric cancer

W Liu, Y Li, S Feng, Y Guan, Y Cao - The journal of biochemistry, 2020 - academic.oup.com
Gastric cancer is one of the most common types of carcinoma with a threat to global health.
MicroRNA-760 (miR-760) was significantly down-regulated in the primary tumour of patients …

Role of microRNAs in atrial fibrillation: new insights and perspectives

KH Shi, H Tao, JJ Yang, JX Wu, SS Xu, HY Zhan - Cellular signalling, 2013 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNA molecules that negatively regulate gene
expression of their targets at the post-transcriptional levels. They typically affect the mRNA …

[HTML][HTML] Up-regulation of miRNA-21 expression promotes migration and proliferation of Sca-1+ cardiac stem cells in mice

Q Zhou, Q Sun, Y Zhang, F Teng… - Medical science monitor …, 2016 - ncbi.nlm.nih.gov
Background This study, by regulating the expression level of microRNA-21 (miRNA-21) in
antigen-1+(Sca-1+) cardiac stem cells (CSCs), examined the role of miRNA-21 in migration …