Long-acting PLGA microspheres: advances in excipient and product analysis toward improved product understanding
Poly (lactic-co-glycolic acid)(PLGA) microspheres are a sustained-release drug delivery
system with several successful commercial products used for the treatment of a variety of …
system with several successful commercial products used for the treatment of a variety of …
Glass transition temperature of PLGA particles and the influence on drug delivery applications
G Liu, K McEnnis - Polymers, 2022 - mdpi.com
Over recent decades, poly (lactic-co-glycolic acid)(PLGA) based nano-and micro-drug
delivery vehicles have been rapidly developed since PLGA was approved by the Food and …
delivery vehicles have been rapidly developed since PLGA was approved by the Food and …
Evolution of drug delivery systems: From 1950 to 2020 and beyond
H Park, A Otte, K Park - Journal of Controlled Release, 2022 - Elsevier
Modern drug delivery technology began in 1952 with the advent of the Spansule® sustained-
release capsule technology, which can deliver a drug for 12 h after oral administration …
release capsule technology, which can deliver a drug for 12 h after oral administration …
[HTML][HTML] A review of existing strategies for designing long-acting parenteral formulations: Focus on underlying mechanisms, and future perspectives
The need for long-term treatments of chronic diseases has motivated the widespread
development of long-acting parenteral formulations (LAPFs) with the aim of improving drug …
development of long-acting parenteral formulations (LAPFs) with the aim of improving drug …
Potential roles of the glass transition temperature of PLGA microparticles in drug release kinetics
Poly (lactic-co-glycolic acid)(PLGA) has been used for long-acting injectable drug delivery
systems for more than 30 years. The factors affecting the properties of PLGA formulations …
systems for more than 30 years. The factors affecting the properties of PLGA formulations …
Patient-centric long-acting injectable and implantable Platforms─ An industrial perspective
The increasing focus on patient centricity in the pharmaceutical industry over the past
decade and the changing healthcare landscape, driven by factors such as increased access …
decade and the changing healthcare landscape, driven by factors such as increased access …
[HTML][HTML] An overview of the production methods for core–shell microspheres for parenteral controlled drug delivery
RS van der Kooij, R Steendam, HW Frijlink… - European Journal of …, 2022 - Elsevier
Core-shell microspheres hold great promise as a drug delivery system because they offer
several benefits over monolithic microspheres in terms of release kinetics, for instance a …
several benefits over monolithic microspheres in terms of release kinetics, for instance a …
[HTML][HTML] Biofunctionalization of 3D printed collagen with bevacizumab-loaded microparticles targeting pathological angiogenesis
Pathological angiogenesis is a crucial attribute of several chronic diseases such as cancer,
age-related macular degeneration, and osteoarthritis (OA). In the case of OA, pathological …
age-related macular degeneration, and osteoarthritis (OA). In the case of OA, pathological …
Long-acting injectable PLGA/PLA depots for leuprolide acetate: successful translation from bench to clinic
SR Abulateefeh - Drug Delivery and Translational Research, 2023 - Springer
The excellent properties of polyesters combined with their ease of synthesis and
modification enabled their wide use in the pharmaceutical industry. This has been translated …
modification enabled their wide use in the pharmaceutical industry. This has been translated …
Polylactide perspectives in biomedicine: from novel synthesis to the application performance
The incessant developments in the pharmaceutical and biomedical fields, particularly,
customised solutions for specific diseases with targeted therapeutic treatments, require the …
customised solutions for specific diseases with targeted therapeutic treatments, require the …