Overcoming endosomal/lysosomal barriers: Advanced strategies for cytosolic siRNA delivery

R Li, M Zhu, X Hu, J Chen, F Yu, S Barth, L Sun… - Chinese Chemical …, 2024 - Elsevier
Small interfering RNAs (siRNA) provide a novel and highly specific therapy due to their
ability to effectively silence target genes, to date six siRNA therapeutics are approved for …

AI-Driven Design of Cell-Penetrating Peptides for Therapeutic Biotechnology

H Ma, X Zhou, Z Zhang, Z Weng, G Li, Y Zhou… - International Journal of …, 2024 - Springer
Abstract Background Cell-penetrating peptides (CPPs) are short sequences of amino acids,
typically ranging from 5 to 30 residues, known for their ability to penetrate cell membranes …

Coassembly of Cell-Penetrating Peptide Octaarginine with Acetazolamide: Emergent Interactions with E. coli

R Choubey, M Chatterjee, PK Pandey, A Mishra… - ACS …, 2024 - ACS Publications
The investigation of established pharmaceutical agents for recalibrating usage strongly
supplements new drug development. In this work, we have prepared coassembled …