Advanced glycation end products (AGEs) and their receptor have been implicated in the
progressions of many intractable diseases, such as diabetes and atherosclerosis, and are …

Advanced glycation endproducts (AGEs) form by Maillard-reactions after initial binding of
aldehydes with amines or amides in heated foods or in living organisms. The mechanisms of …

The receptor for advanced glycation end-product (RAGE) is the signal transduction receptor
which senses a variety of signalling molecules including advanced glycation end products …

Gliptins have been recently shown to conquer neuronal degeneration in cell cultures via
modulating glucagon‐like peptide (GLP)‐1. This peptide produced in the gut not only …

Brain aging is characterized by several structural, biochemical and molecular changes
which can vary among different individuals and can be influenced by genetic, environmental …

Diabetic foot ulcer (DFU) is a debilitating and severe manifestation of uncontrolled and
prolonged diabetes that presents as ulceration, usually located on the plantar aspect of the …

Alzheimer's disease (AD) is a common form of dementia in aged people, which is defined by
two pathological characteristics: β-amyloid protein (Aβ) deposition and tau …

Receptor for advanced glycation end products (RAGE) is an immunoglobulin-like receptor
present on cell surface. RAGE binds to an array of structurally diverse ligands, acts as a …

Nicotine contained in cigarette smoke contributes to the onset of several diseases, including
osteoporosis, whose emerging pathogenic mechanism is associated with osteoblasts …

Advanced glycation end products (AGEs) are naturally occurring molecules that start to
accumulate from embryonic developmental stages and form as part of normal ageing. When …