A review of current practice in the design and analysis of extremely small stepped-wedge cluster randomized trials
Background/Aims Stepped-wedge cluster randomized trials tend to require fewer clusters
than standard parallel-arm designs due to the switches between control and intervention …
than standard parallel-arm designs due to the switches between control and intervention …
Evaluating the performance of Bayesian and restricted maximum likelihood estimation for stepped wedge cluster randomized trials with a small number of clusters
Background Stepped wedge trials are an appealing and potentially powerful cluster
randomized trial design. However, they are frequently implemented with a small number of …
randomized trial design. However, they are frequently implemented with a small number of …
Pragmatic cluster randomized trial to evaluate effectiveness and implementation of EHR-facilitated collaborative symptom control in cancer (E2C2): addendum
J Herrin, LJ Finney Rutten, KJ Ruddy, K Kroenke… - Trials, 2023 - Springer
We previously described the hypotheses, outcomes, design, and analysis for E2C2, a
pragmatic stepped-wedge trial to assess an intervention to improve symptom control in …
pragmatic stepped-wedge trial to assess an intervention to improve symptom control in …
Implementation of increased physical therapy intensity for improving walking after stroke: Walk'n watch protocol for a multisite stepped-wedge cluster-randomized …
Rationale: Clinical practice guidelines support structured, progressive protocols for
improving walking after stroke. Yet, practice is slow to change, evidenced by the little amount …
improving walking after stroke. Yet, practice is slow to change, evidenced by the little amount …
A Bayesian adaptive design approach for stepped-wedge cluster randomized trials
Background: The Bayesian group sequential design has been applied widely in clinical
studies, especially in Phase II and III studies. It allows early termination based on …
studies, especially in Phase II and III studies. It allows early termination based on …
Advancing Stepped Wedge Cluster Randomized Trials Analysis: Bayesian Hierarchical Penalized Spline Models for Immediate and Time-Varying Intervention Effects
Stepped wedge cluster randomized trials (SWCRTs) often face challenges with potential
confounding by time trends. Traditional frequentist methods can fail to provide adequate …
confounding by time trends. Traditional frequentist methods can fail to provide adequate …
Priors from Envisioned Posterior Judgments: A Novel Elicitation Approach With Application to Bayesian Clinical Trials
The uptake of formalized prior elicitation from experts in Bayesian clinical trials has been
limited, largely due to the challenges associated with complex statistical modeling, the lack …
limited, largely due to the challenges associated with complex statistical modeling, the lack …
The SToP (See, Treat, Prevent) Skin Sores and Scabies Trial-a stepped wedge cluster randomised trial for skin disease control in remote Western Australia: Statistical …
The SToP trial is an (open-cohort) stepped-wedge cluster randomised trial (SWCRT) that
aims to evaluate a skin health programme comprising three intervention components (1) …
aims to evaluate a skin health programme comprising three intervention components (1) …