Burkholderia pseudomallei and melioidosis

EM Meumann, D Limmathurotsakul… - Nature Reviews …, 2024 - nature.com
Burkholderia pseudomallei, the causative agent of melioidosis, is found in soil and water of
tropical and subtropical regions globally. Modelled estimates of the global burden predict …

[HTML][HTML] Melioidosis

WJ Wiersinga, HS Virk, AG Torres, BJ Currie… - Nature reviews Disease …, 2018 - nature.com
Burkholderia pseudomallei is a Gram-negative environmental bacterium and the
aetiological agent of melioidosis, a life-threatening infection that is estimated to account …

Global and regional dissemination and evolution of Burkholderia pseudomallei

C Chewapreecha, MTG Holden, M Vehkala… - Nature …, 2017 - nature.com
The environmental bacterium Burkholderia pseudomallei causes an estimated 165,000
cases of human melioidosis per year worldwide and is also classified as a biothreat agent …

[HTML][HTML] Melioidosis: clinical impact and public health threat in the tropics

R Perumal Samy, BG Stiles, G Sethi… - PLoS neglected tropical …, 2017 - journals.plos.org
This review briefly summarizes the geographical distribution and clinical impact of
melioidosis, especially in the tropics. Burkholderia pseudomallei (a gram-negative …

Biofilm and motility in response to environmental and host‐related signals in Gram negative opportunistic pathogens

E Rossi, M Paroni, P Landini - Journal of Applied Microbiology, 2018 - academic.oup.com
Most bacteria can switch between a planktonic, sometimes motile, form and a biofilm mode,
in which bacterial cells can aggregate and attach to a solid surface. The transition between …

The Type VI secretion system spike protein VgrG5 mediates membrane fusion during intercellular spread by pseudomallei group Burkholderia species

IJ Toesca, CT French, JF Miller - Infection and immunity, 2014 - Am Soc Microbiol
Pseudomallei group Burkholderia species are facultative intracellular parasites that spread
efficiently from cell to cell by a mechanism involving the fusion of adjacent cell membranes …

Melioidosis: molecular aspects of pathogenesis

JK Stone, D DeShazer, PJ Brett… - Expert review of anti …, 2014 - Taylor & Francis
Burkholderia pseudomallei is a gram-negative bacterium that causes melioidosis, a
multifaceted disease that is highly endemic in southeast Asia and northern Australia. This …

[HTML][HTML] A novel contact-independent T6SS that maintains redox homeostasis via Zn2+ and Mn2+ acquisition is conserved in the Burkholderia pseudomallei complex

D DeShazer - Microbiological research, 2019 - Elsevier
The Burkholderia pseudomallei complex consists of six phylogenetically related Gram-
negative bacterial species that include environmental saprophytes and mammalian …

[HTML][HTML] Intracellular replication of the well-armed pathogen Burkholderia pseudomallei

SJ Willcocks, CC Denman, HS Atkins… - Current opinion in …, 2016 - Elsevier
Highlights•Burkholderia pseudomallei (BPS) possess a variety of virulence factors that
facilitate survival at different stages of intracellular infection in a variety of cell types.•At the …

Co-evolutionary Signals Identify Burkholderia pseudomallei Survival Strategies in a Hostile Environment

C Chewapreecha, J Pensar, S Chattagul… - Molecular Biology …, 2022 - academic.oup.com
The soil bacterium Burkholderia pseudomallei is the causative agent of melioidosis and a
significant cause of human morbidity and mortality in many tropical and subtropical …