Current advance of nanotechnology in diagnosis and treatment for malignant tumors
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …
[HTML][HTML] Cell-penetrating peptides in protein mimicry and cancer therapeutics
Extensive research has been undertaken in the pursuit of anticancer therapeutics. Many
anticancer drugs require specificity of delivery to cancer cells, whilst sparing healthy tissue …
anticancer drugs require specificity of delivery to cancer cells, whilst sparing healthy tissue …
Chiral protein supraparticles for tumor suppression and synergistic immunotherapy: an enabling strategy for bioactive supramolecular chirality construction
The design of bioactive supramolecular chirality is always hampered by the lack of feasible
schemes to assigned specific biological activities. Herein, we developed a “mirror-image …
schemes to assigned specific biological activities. Herein, we developed a “mirror-image …
[HTML][HTML] Turning chiral peptides into a racemic supraparticle to induce the self-degradation of MDM2
Introduction Chirality is immanent in nature, and chiral molecules can achieve their
pharmacological action through chiral matching with biomolecules and molecular …
pharmacological action through chiral matching with biomolecules and molecular …
Advances in drug delivery for post-surgical cancer treatment
Surgery remains a primary modality of treatment for the majority of solid tumor malignancies.
While advancements in surgical technique and instrumentation have improved the quality of …
While advancements in surgical technique and instrumentation have improved the quality of …
Biodegradable two-dimensional nanomaterials for cancer theranostics
N Ni, X Zhang, Y Ma, J Yuan, D Wang, G Ma… - Coordination Chemistry …, 2022 - Elsevier
Abstract Two-dimensional (2D) nanomaterials hold great potential in cancer application. At
present, the research of 2D nanomaterials mainly focuses on elucidating their unique …
present, the research of 2D nanomaterials mainly focuses on elucidating their unique …
[HTML][HTML] Turing milk into pro-apoptotic oral nanotherapeutic: De novo bionic chiral-peptide supramolecule for cancer targeted and immunological therapy
W He, Z Zhang, W Yang, X Zheng, W You, Y Yao… - Theranostics, 2022 - ncbi.nlm.nih.gov
Chirality in biomolecules is ubiquitous in our world, but oral nanomedicines constructed from
chiral peptides are extremely rare, principally because of the immature nanofabrication and …
chiral peptides are extremely rare, principally because of the immature nanofabrication and …
Reinvigoration of cytotoxic T lymphocytes in microsatellite instability-high colon adenocarcinoma through lysosomal degradation of PD-L1
Compensation and intracellular storage of PD-L1 may compromise the efficacy of antibody
drugs targeting the conformational blockade of PD1/PD-L1 on the cell surface. Alternative …
drugs targeting the conformational blockade of PD1/PD-L1 on the cell surface. Alternative …
[HTML][HTML] A de novo dual-targeting supramolecular self-assembly peptide against pulmonary metastasis of melanoma
Despite recent advances in treatment, overall survival rates for metastatic melanoma,
especially those that invade the lungs, continue to be low, with 5-year survival rates of only …
especially those that invade the lungs, continue to be low, with 5-year survival rates of only …
A bionic nano-band-aid constructed by the three-stage self-assembly of peptides for rapid liver hemostasis
Critical challenges remain in trauma emergency and surgical procedures involving liver
bleeding, particularly in perforating wounds that cannot be pressed and large wounds that …
bleeding, particularly in perforating wounds that cannot be pressed and large wounds that …