The prevalence of kidney diseases is emerging as a public health problem. Stem cells
(SCs), currently considered as a promising tool for therapeutic application, have aroused …

Despite growing interest and effort, a consensus has yet to be reached in regards to the
identification of adult renal stem cells. Organ complexity and low turnover of renal cells has …

Kidney-derived c-Kit+ cells exhibit progenitor/stem cell properties in vitro (self-renewal
capacity, clonogenicity, and multipotentiality). These cells can regenerate epithelial tubular …

Acute kidney injury (AKI) remains a significant clinical problem through its diverse etiologies,
the challenges of robust measurements of injury and recovery, and its progression to chronic …

Abstract Background Label-retaining cells (LRCs) have been recognized as rare stem and
progenitor-like cells, but their complex biological features in renal repair at the cellular level …

ONE OF THE OLDEST ASSAYS for identifying stem cells, DNA analog pulse-chase studies
date back more than 60 years (2). The concept derives from the observation that stem cells …

The mammalian kidney has extensive repair capacity; however, identifying adult renal stem
cells has proven elusive. We applied an epigenetic marker of foetal cell origin (FCO) in …

The mammalian kidney has extensive repair capacity; however, identifying adult renal stem
cells has proven elusive. We applied an epigenetic marker of foetal cell origin (FCO) in …

4. 其他干细胞样细胞: 有许多学者发现分布在肾脏中的rks56 细胞, 干细胞抗原1 (Sca⁃ 1)
阳性细胞, CD45-细胞和边缘细胞(SP cells) 等细胞都具有干细胞样细胞特性[23-25] …

The role of Wnt signaling in autosomal dominant polycystic kidney disease (ADPKD) has
been a topic of interest for many years due to the presence of renal cysts in mouse models of …