Effects of prenatal hypoxia on nervous system development and related diseases

B Wang, H Zeng, J Liu, M Sun - Frontiers in neuroscience, 2021 - frontiersin.org
The fetal origins of adult disease (FOAD) hypothesis, which was proposed by David Barker
in the United Kingdom in the late 1980s, posited that adult chronic diseases originated from …

Molecular mechanisms of neonatal brain injury

C Thornton, CI Rousset, A Kichev… - Neurology research …, 2012 - Wiley Online Library
Fetal/neonatal brain injury is an important cause of neurological disability. Hypoxia‐
ischemia and excitotoxicity are considered important insults, and, in spite of their acute …

Prenatal THC exposure induces long-term, sex-dependent cognitive dysfunction associated with lipidomic and neuronal pathology in the prefrontal cortex …

MH Sarikahya, SL Cousineau, M De Felice… - Molecular …, 2023 - nature.com
With increasing maternal cannabis use, there is a need to investigate the lasting impact of
prenatal exposure to Δ9-tetrahydrocannabinol (THC), the main psychotropic compound in …

Animal models for neonatal brain injury induced by hypoxic ischemic conditions in rodents

N Hamdy, S Eide, HS Sun, ZP Feng - Experimental Neurology, 2020 - Elsevier
Neonatal hypoxia-ischemia and resulting encephalopathies are of significant concern.
Intrapartum asphyxia is a leading cause of neonatal death globally. Among surviving infants …

[HTML][HTML] Impact of perinatal hypoxia on the developing brain

M Piešová, M Mojmír - Physiological research, 2020 - ncbi.nlm.nih.gov
Perinatal hypoxia is still one of the greatest threats to the newborn child, even in developed
countries. However, there is a lack of works which summarize up-to-date information about …

[HTML][HTML] Prenatal tetrahydrocannabinol and cannabidiol exposure produce sex-specific pathophysiological phenotypes in the adolescent prefrontal cortex and …

MV DeVuono, MG Nashed, MH Sarikahya… - Neurobiology of …, 2024 - Elsevier
Clinical and preclinical evidence has demonstrated an increased risk for neuropsychiatric
disorders following prenatal cannabinoid exposure. However, given the phytochemical …

Atypical fetal development: Fetal alcohol syndrome, nutritional deprivation, teratogens, and risk for neurodevelopmental disorders and psychopathology

MK Georgieff, PV Tran, ES Carlson - Development and …, 2018 - cambridge.org
Accumulating evidence indicates that the fetal environment plays an important role in brain
development and sets the brain on a trajectory across the life span. An abnormal fetal …

Prenatal ischemia deteriorates white matter, brain organization, and function: implications for prematurity and cerebral palsy

JO Coq, M Delcour, VS Massicotte… - … Medicine & Child …, 2016 - Wiley Online Library
Cerebral palsy (CP) describes a group of neurodevelopmental disorders of posture and
movement that are frequently associated with sensory, behavioral, and cognitive …

Transcriptomic regulations in oligodendroglial and microglial cells related to brain damage following fetal growth restriction

A Rideau Batista Novais, H Pham, Y Van de Looij… - Glia, 2016 - Wiley Online Library
Fetal growth restriction (FGR) is a major complication of human pregnancy, frequently
resulting from placental vascular diseases and prenatal malnutrition, and is associated with …

Behavioral and histological outcomes following neonatal HI injury in a preterm (P3) and term (P7) rodent model

M Alexander, H Garbus, AL Smith… - Behavioural Brain …, 2014 - Elsevier
Hypoxia–ischemia (HI) occurs when blood and/or oxygen delivery to the brain is
compromised. HI injuries can occur in infants born prematurely (< 37 weeks gestational age) …