How to build a cognitive map

JCR Whittington, D McCaffary, JJW Bakermans… - Nature …, 2022 - nature.com
Learning and interpreting the structure of the environment is an innate feature of biological
systems, and is integral to guiding flexible behaviors for evolutionary viability. The concept of …

[HTML][HTML] Representational drift: Emerging theories for continual learning and experimental future directions

LN Driscoll, L Duncker, CD Harvey - Current Opinion in Neurobiology, 2022 - Elsevier
Recent work has revealed that the neural activity patterns correlated with sensation,
cognition, and action often are not stable and instead undergo large scale changes over …

Building an allocentric travelling direction signal via vector computation

C Lyu, LF Abbott, G Maimon - Nature, 2022 - nature.com
Many behavioural tasks require the manipulation of mathematical vectors, but, outside of
computational models,,,,,–, it is not known how brains perform vector operations. Here we …

Time and experience differentially affect distinct aspects of hippocampal representational drift

N Geva, D Deitch, A Rubin, Y Ziv - Neuron, 2023 - cell.com
Hippocampal activity is critical for spatial memory. Within a fixed, familiar environment,
hippocampal codes gradually change over timescales of days to weeks—a phenomenon …

Representational drift in primary olfactory cortex

CE Schoonover, SN Ohashi, R Axel, AJP Fink - Nature, 2021 - nature.com
Perceptual constancy requires the brain to maintain a stable representation of sensory input.
In the olfactory system, activity in primary olfactory cortex (piriform cortex) is thought to …

[HTML][HTML] The population doctrine in cognitive neuroscience

RB Ebitz, BY Hayden - Neuron, 2021 - cell.com
A major shift is happening within neurophysiology: a population doctrine is drawing level
with the single-neuron doctrine that has long dominated the field. Population-level ideas …

Active experience, not time, determines within-day representational drift in dorsal CA1

D Khatib, A Ratzon, M Sellevoll, O Barak, G Morris… - Neuron, 2023 - cell.com
Memories of past events can be recalled long after the event, indicating stability. But new
experiences are also integrated into existing memories, indicating plasticity. In the …

Thirst regulates motivated behavior through modulation of brainwide neural population dynamics

WE Allen, MZ Chen, N Pichamoorthy, RH Tien… - Science, 2019 - science.org
INTRODUCTION Motivational drives are internal states that can explain why animals
adaptively display distinct behaviors in response to the same external stimulus …

Temporal evolution of cortical ensembles promoting remote memory retrieval

LA DeNardo, CD Liu, WE Allen, EL Adams… - Nature …, 2019 - nature.com
Memories of fearful events can last a lifetime. The prelimbic (PL) cortex, a subregion of
prefrontal cortex, plays a critical role in fear memory retrieval over time. Most studies have …

Ion channel degeneracy, variability, and covariation in neuron and circuit resilience

JM Goaillard, E Marder - Annual review of neuroscience, 2021 - annualreviews.org
The large number of ion channels found in all nervous systems poses fundamental
questions concerning how the characteristic intrinsic properties of single neurons are …