There is increasing appreciation that non-neuronal cells contribute to the initiation,
progression and pathology of diverse neurodegenerative disorders. This Review focuses on …

Glial fibrillary acidic protein (GFAP) is the hallmark intermediate filament (IF; also known as
nanofilament) protein in astrocytes, a main type of glial cells in the central nervous system …

Astrocytes are the most abundant cells in the central nervous system (CNS) that provide
nutrients, recycle neurotransmitters, as well as fulfill a wide range of other homeostasis …

Glial fibrillary acidic protein (GFAP) is the main intermediate filament protein in mature
astrocytes, but also an important component of the cytoskeleton in astrocytes during …

Astrocytes maintain the homeostasis of the central nervous system (CNS) by eg recycling of
neurotransmitters and providing nutrients to neurons. Astrocytes function also as key …

Prions are unprecedented infectious pathogens that cause a group of invariably fatal
neurodegenerative diseases by an entirely novel mechanism. Prion diseases may present …

It is now well established that the glial fibrillary acidic protein (GFAP) is the principal 8–9 nm
intermediate filament in mature astrocytes of the central nervous system (CNS). Over a …

Astrocytes become activated (reactive) in response to many CNS pathologies, such as
stroke, trauma, growth of a tumor, or neurodegenerative disease. The process of astrocyte …

For several decades, the reactive gliosis that occurs after an injury to the CNS has been
considered one of the major impediments to axonal regeneration. Nevertheless, recent …

Establishing the cellular identity in vivo of adult multipotent neural progenitors is
fundamental to understanding their biology. We used two transgenic strategies to determine …