Dose–volume effects for normal tissues in external radiotherapy: pelvis

C Fiorino, R Valdagni, T Rancati… - Radiotherapy and …, 2009 - Elsevier
A great deal of quantitative information regarding the dose–volume relationships of pelvic
organs at risk has been collected and analysed over the last 10 years. The need to improve …

Chronic radiation proctitis: tricks to prevent and treat

BGL Vanneste, L Van De Voorde, RJ de Ridder… - International journal of …, 2015 - Springer
Objective The purpose of this study was to give an overview of the measures used to prevent
chronic radiation proctitis (CRP) and to provide an algorithm for the treatment of CRP …

Intensity-modulated radiation therapy, proton therapy, or conformal radiation therapy and morbidity and disease control in localized prostate cancer

NC Sheets, GH Goldin, AM Meyer, Y Wu, YK Chang… - Jama, 2012 - jamanetwork.com
Context There has been rapid adoption of newer radiation treatments such as intensity-
modulated radiation therapy (IMRT) and proton therapy despite greater cost and limited …

Hypofractionated versus conventionally fractionated radiotherapy for patients with prostate cancer (HYPRO): acute toxicity results from a randomised non-inferiority …

S Aluwini, F Pos, E Schimmel, E van Lin, S Krol… - The Lancet …, 2015 - thelancet.com
Background In 2007, we began the randomised phase 3 multicentre HYPRO trial to
investigate the effect of hypofractionated radiotherapy compared with conventionally …

Acute toxicity of curative radiotherapy for intermediate-and high-risk localised prostate cancer in the EORTC trial 22991

O Matzinger, F Duclos, A Van den Bergh… - European journal of …, 2009 - Elsevier
INTRODUCTION: This trial randomly assessed short-term adjuvant hormonal therapy added
to radiotherapy (RT) for intermediate-and high-risk (UICC 1997 cT2a or cT1b-c with high …

Patient‐reported outcomes after 3‐dimensional conformal, intensity‐modulated, or proton beam radiotherapy for localized prostate cancer

PJ Gray, JJ Paly, BY Yeap, MG Sanda, HM Sandler… - Cancer, 2013 - Wiley Online Library
BACKGROUND: Recent studies have suggested differing toxicity patterns for patients with
prostate cancer who receive treatment with 3‐dimensional conformal radiotherapy (3DCRT) …

Dose–surface maps identifying local dose–effects for acute gastrointestinal toxicity after radiotherapy for prostate cancer

RC Wortel, MG Witte, UA van der Heide, FJ Pos… - Radiotherapy and …, 2015 - Elsevier
Background and purpose We evaluated dose distributions in the anorectum and its relation
to acute gastrointestinal toxicities using dose surface maps in an image-guided (IG) IMRT …

Use of machine learning methods for prediction of acute toxicity in organs at risk following prostate radiotherapy

A Pella, R Cambria, M Riboldi… - Medical …, 2011 - Wiley Online Library
Purpose: The goal of this study is to investigate the advantages of large scale optimization
methods vs conventional classification techniques in predicting acute toxicity for urinary …

Clinical and dosimetric predictors of late rectal toxicity after conformal radiation for localized prostate cancer: results of a large multicenter observational study

G Fellin, C Fiorino, T Rancati, V Vavassori… - Radiotherapy and …, 2009 - Elsevier
PURPOSE: Assessing the predictors of late rectal toxicity after high-dose conformal
radiotherapy for prostate cancer. METHODS: One thousand one hundred thirty-two patients …

The ESTRO Breur Lecture 2009. From population to voxel-based radiotherapy: exploiting intra-tumour and intra-organ heterogeneity for advanced treatment of non …

P Lambin, SF Petit, HJWL Aerts, WJC van Elmpt… - Radiotherapy and …, 2010 - Elsevier
Evidence is accumulating that radiotherapy of non-small cell lung cancer patients can be
optimized by escalating the tumour dose until the normal tissue tolerances are met. To …