Alzheimer's disease: Molecular aspects and treatment opportunities using herbal drugs

S Thakral, A Yadav, V Singh, M Kumar, P Kumar… - Ageing Research …, 2023 - Elsevier
Abstract Alzheimer's disease (AD), also called senile dementia, is the most common
neurological disorder. Around 50 million people, mostly of advanced age, are suffering from …

Targeting disorders in unstructured and structured proteins in various diseases

S Choudhary, M Lopus, RV Hosur - Biophysical Chemistry, 2022 - Elsevier
Intrinsically disordered proteins (IDPs) and intrinsically disordered protein regions (IDPRs)
are proteins and protein segments that usually do not acquire well-defined folded structures …

[HTML][HTML] Chromolaena odorata (Siam weed): A natural reservoir of bioactive compounds with potent anti-fibrillogenic, antioxidative, and cytocompatible properties

FN Eze, TJ Jayeoye - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Protein fibrillation and oxidative damage are closely associated with the development of
many chronic diseases such as Alzheimer's disease, Parkinson's disease and transthyretin …

[HTML][HTML] Aqueous extract of Triphala inhibits cancer cell proliferation through perturbation of microtubule assembly dynamics

S Cheriyamundath, T Mahaddalkar, SN Save… - Biomedicine & …, 2018 - Elsevier
Triphala (Trl) is an ayurvedic formulation used for treating disorders of the digestive,
respiratory, and nervous systems. Its anticancer properties have also been documented. We …

Synergistic antioxidant activity of plant compositions contained in Chatuphalathika herbal recipe: Terminalia chebula Retz. var. chebula, Terminalia arjuna Wight and …

J Suksaeree, T Wunnakup, C Monton - Advances in Traditional Medicine, 2022 - Springer
The work sought to investigate, using response surface analysis, the synergistic antioxidant
activity among four plants—Terminalia chebula Retz. var. chebula, Terminalia arjuna Wight …

Unravelling the inhibitory activity of Chlamydomonas reinhardtii sulfated polysaccharides against α-Synuclein fibrillation

S Choudhary, SN Save, SL Vavilala - Scientific Reports, 2018 - nature.com
Abstract α-Synuclein (α-Syn) is an intrinsically disordered presynaptic protein, whose
aggregation is critically involved in Parkinson's disease (PD). Many of the currently available …

Study on the stability control strategy of Triphala solution based on the balance of physical stability and chemical stabilities

H Huang, S Zhao, X Ke, J Lin, S Huang, R Xu… - … of pharmaceutical and …, 2018 - Elsevier
Triphala is a well-known prescription in Indian Ayurveda and TCM medicine for its great
effect on gingivitis and hyperlipidemia. However, its solution is unstable for the containing of …

Formulation Development of Directly Compressible Tablets Incorporating Trisamo Extract With Synergistic Antioxidant Activity

J Suksaeree, T Wunnakup, N Chankana… - … Journal of Food …, 2024 - Wiley Online Library
This work investigates the synergistic antioxidant activity of the compositions of Trisamo
(TSM) herbal formula containing the dried fruits of Terminalia chebula, Terminalia arjuna …

Investigation of the interaction of herbal ingredients contained in Triphala recipe using simplex lattice design: Chemical analysis point of view

C Monton, T Wunnakup, J Suksaeree… - … Journal of Food …, 2020 - Wiley Online Library
The aim of this work was to investigate the interaction of herbal ingredients contained in
Triphala recipe (Terminalia chebula, Terminalia bellirica, and Phyllanthus emblica in equal …

Andrographolide inhibits human serum albumin fibril formations through site-specific molecular interactions

A Basu, S Bhayye, S Kundu, A Das, A Mukherjee - RSC advances, 2018 - pubs.rsc.org
Protein misfolding and fibrillation are the fundamental traits in degenerative diseases like
Alzheimer's, Parkinsonism, and diabetes mellitus. Bioactives such as flavonoids and …