Anosmia and hyposmia, the inability or decreased ability to smell, is estimated to afflict 3–
20% of the population. Risk of olfactory dysfunction increases with old age and may also …

Bardet–Biedl syndrome is a rare autosomal recessive multisystem disorder caused by
defects in genes encoding for proteins that localize to the primary cilium/basal body …

Non-viral gene delivery vectors have lagged far behind viral ones in the current pipeline of
clinical trials of gene therapy nanomedicines. Even when non-viral nanovectors pose less …

Cilia are highly specialized cellular organelles that serve multiple functions in human
development and health. Their central importance in the body is demonstrated by the …

Ciliary disorders, which are also referred to as ciliopathies, are a group of hereditary
disorders that result from dysfunctional cilia. The latter are cellular organelles that stick up …

Alström syndrome (ALMS) is a rare genetic disorder that has been included in the
ciliopathies group, in the last few years. Ciliopathies are a growing group of diseases …

Olfaction plays a critical role in several aspects of life. Olfactory disorders are very common
in the general population, and can lead to malnutrition, weight loss, food poisoning …

Olfactory dysfunction is a pervasive but underappreciated health concern that affects
personal safety and quality of life. Patients with olfactory dysfunctions have limited …

Molecular variant interpretation lacks disease gene‐specific cohorts for determining variant
enrichment in disease versus healthy populations. To address the molecular etiology of …

Directing stem cell lineage commitment prevails as the holy grail of translational stem cell
research, particularly to those interested in the application of mesenchymal stem cells and …