Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of
coronavirus disease 2019 (COVID-19), has resulted in a pandemic that has had widespread …

Monitoring SARS-CoV-2 spread and evolution through genome sequencing is essential in
handling the COVID-19 pandemic. Here, we sequenced 892 SARS-CoV-2 genomes …

The IFN system constitutes a powerful antiviral defense machinery. Consequently, effective
IFN responses protect against severe COVID-19 and exogenous IFNs inhibit SARS-CoV-2 …

As the COVID‐19 pandemic grows, several therapeutic candidates are being tested or
undergoing clinical trials. Although prophylactic vaccination against SARS‐CoV‐2 infection …

Monitoring SARS-CoV-2 spread and evolution through genome sequencing is essential in
handling the COVID-19 pandemic. The availability of patient hospital records is crucial for …

The COVID-19 pandemic has caused significant morbidity and mortality worldwide. The
emergence of the Alpha and Delta variants of SARS-CoV-2 has led to a renewed interest in …

Macrophages detect invading microorganisms via pattern recognition receptors that
recognize pathogen-associated molecular patterns, or via sensing the activity of virulence …

Interferons (IFNs) are a key component of the innate antiviral immunity and are generally
implicated in protective host immune responses. Here, I discuss the central role of IFNs …

The recent pandemic was caused by the emergence of a new human pathogen, SARS-CoV-
2. While the rapid development of many vaccines provided an end to the immediate crisis …

Coronavirus disease 2019 is known to be regulated by multiple factors such as delayed
immune response, impaired T cell activation, and elevated levels of proinflammatory …