Identification and management of patients at high bleeding risk undergoing percutaneous
coronary intervention are of major importance, but a lack of standardization in defining this …

The rapidly declining prevalence of Helicobacter pylori infection and widespread use of
potent anti-secretory drugs means peptic ulcer disease has become substantially less …

Abstract The Japanese Society of Gastroenterology (JSGE) revised the third edition of
evidence-based clinical practice guidelines for peptic ulcer disease in 2020 and created an …

Peptic ulcer is a chronic disease affecting up to 10% of the world's population. The formation
of peptic ulcers depends on the presence of gastric juice pH and the decrease in mucosal …

Peptic ulcer disease (PUD) is a common condition that both primary care providers and
gastroenterologists encounter. Symptoms of peptic ulcer disease are variable and may …

Background The introduction of proton pump inhibitors (PPIs) into clinical practice has
revolutionized the management of acid-related diseases. Studies in primary care and …

The stomach is traditionally regarded as a hollow muscular sac that initiates the second
phase of digestion. Yet this simple view ignores the fact that it is the most sophisticated …

Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen have a long history of safe
and effective use as both prescription and over-the-counter (OTC) analgesics/antipyretics …

Ibuprofen first came to market about 50 years ago and rapidly moved to over-the-counter
(OTC) sales. In April 2019, the National Agency for the Safety of Medicines and Health …

Non-variceal upper gastrointestinal bleeding (NVUGIB) is bleeding that develops in the
oesophagus, stomach or proximal duodenum. Peptic ulcers, caused by Helicobacter pylori …