Biosafety is the primary concern in clinical translation of nanomedicine. As an intrinsic
ingredient of human blood without immunogenicity and encouraged by its successful clinical …

Prodrugs are cunning derivatives of therapeutic agents designed to improve the
pharmacokinetics profile of the drug. Within a prodrug, pharmacological activity of the drug is …

Among serum proteins albumin and transferrin have attracted the most interest as drug
carriers in the past two decades. Prior to that, their potential use was overshadowed by the …

Albumin is a biocompatible, non-immunogenic and versatile drug carrier system. It has been
widely used to extend the half-life, enhance stability, provide protection from degradation …

The prostate-specific antigen (PSA) blood test is the accepted biomarker of tumor
recurrence. PSA levels in serum correlate with disease progression, though its diagnostic …

A novel pH and redox dual-responsive prodrug nanogel was prepared by an inverse
nanoprecipitation method, which is mild and surfactant free, and based on a thiol-disulfide …

The design of novel antitumor agents allowing the destruction of malignant cells while
sparing healthy tissues is one of the major challenges in medicinal chemistry. In this context …

To achieve effective chemotherapy, many types of drug delivery systems have been
developed for the specific environments in tumor tissues. Polymer–drug conjugates are …

Developing new therapeutic strategies that damage tumour cells without harming normal
tissues is among the primary obstacles in chemotherapy. In this study, a novel β …

Prostate cancer (PC) is the most prevalent male urogenital cancer worldwide. PC patients
presenting an advanced or metastatic cancer succumb to the disease, even after therapeutic …