Importance Although magnetic resonance imaging (MRI) is useful for monitoring disease
dissemination in space and over time and excluding multiple sclerosis (MS) mimics, there …

Animal models of multiple sclerosis (MS), specifically experimental autoimmune
encephalomyelitis (EAE), have been used extensively to develop anti-inflammatory …

Objective In multiple sclerosis (MS), MRI measures at the whole brain or regional level are
only modestly associated with disability, while network-based measures are emerging as …

Background: In multiple sclerosis (MS), thalamic integrity is affected directly by
demyelination and neuronal loss, and indirectly by gray/white matter lesions outside the …

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) that
affects nearly 2.8 million people each year. MS distinguishes three main types: relapsing …

Background Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating, degenerative
disease of the central nervous system that affects approximately 2.8 million people …

Background Although reduced thalamic volume is associated with multiple sclerosis (MS)‐
related clinical impairment, the role of individual thalamic nuclei remains poorly understood …

Background: Thalamic atrophy is proposed to be a major predictor of disability progression
in multiple sclerosis (MS), while thalamic function remains understudied. Objectives: To …

Introduction Multiple Sclerosis (MS) is a chronic neurodegenerative disorder that affects the
central nervous system (CNS) and results in progressive clinical disability and cognitive …

Background and purpose In an era of individualized multiple sclerosis (MS) patient
management, biomarkers for accurate prediction of future clinical outcomes are needed. We …