Cancer-associated SNPs in bacteria: lessons from Helicobacter pylori

B Linz, H Sticht, N Tegtmeyer, S Backert - Trends in Microbiology, 2024 - cell.com
Several single-nucleotide polymorphisms (SNPs) in human chromosomes are known to
predispose to cancer. However, cancer-associated SNPs in bacterial pathogens were …

Infection of Helicobacter pylori contributes to the progression of gastric cancer through ferroptosis

Y Liu, R Miao, J Xia, Y Zhou, J Yao, S Shao - Cell Death Discovery, 2024 - nature.com
Helicobacter pylori (H. pylori) is a gram-negative pathogen that colonizes gastric epithelial
cells, and its chronic infection is the primary risk factor for the development of gastric cancer …

Cultivation and molecular characterization of viable Helicobacter pylori from the root canal of 170 deciduous teeth of children

W Elger, N Tegtmeyer, M Rohde, B Linz… - Cell Communication and …, 2024 - Springer
Helicobacter pylori is a persistent pathogen in the human stomach. However, the proposed
transmission route via the oral cavity is not understood and under intense debate. While …

Two remarkable serine/leucine polymorphisms in Helicobacter pylori: functional importance for serine protease HtrA and adhesin BabA

S Backert, N Tegtmeyer, AHC Horn, H Sticht… - Cell Communication and …, 2024 - Springer
Single nucleotide polymorphisms (SNPs) account for significant genomic variability in
microbes, including the highly diverse gastric pathogen Helicobacter pylori. However, data …

[HTML][HTML] Prevalence of Helicobacter pylori infection in China from 2014-2023: A systematic review and meta-analysis

L Xie, GW Liu, YN Liu, PY Li, XN Hu… - World Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
BACKGROUND Helicobacter pylori (H. pylori) stands as the predominant infectious agent
linked to the onset of gastritis, peptic ulcer diseases, and gastric cancer (GC). Identified as …

Current Knowledge about Gastric Microbiota with Special Emphasis on Helicobacter pylori-Related Gastric Conditions

L Santacroce, S Topi, L Bottalico, IA Charitos… - Current Issues in …, 2024 - mdpi.com
The gastric milieu, because of its very low acidic pH, is very harsh for bacterial growth. The
discovery of Helicobacter pylori (Hp) has opened a new avenue for studies on the gastric …