Acylcarnitines: nomenclature, biomarkers, therapeutic potential, drug targets, and clinical trials

M Dambrova, M Makrecka-Kuka, J Kuka… - Pharmacological …, 2022 - Elsevier
Acylcarnitines are fatty acid metabolites that play important roles in many cellular energy
metabolism pathways. They have historically been used as important diagnostic markers for …

[HTML][HTML] Metabolomics and microbiome profiling as biomarkers in obstructive sleep apnoea: a comprehensive review

X Zhang, S Wang, H Xu, H Yi, J Guan… - European Respiratory …, 2021 - Eur Respiratory Soc
Introduction Obstructive sleep apnoea (OSA) is a common sleep disorder with a high social
and economic burden. Thus, early prediction and diagnosis of OSA are important. Changes …

Obstructive sleep apnea and metabolic syndrome

SQC Giampá, G Lorenzi‐Filho, LF Drager - Obesity, 2023 - Wiley Online Library
Metabolic syndrome (MS) is a heterogeneous condition associated with increased
cardiovascular risk. There is growing evidence from experimental, translational, and clinical …

Metabolomic profiles of sleep-disordered breathing are associated with hypertension and diabetes mellitus development

Y Zhang, B Yu, Q Qi, A Azarbarzin, H Chen… - Nature …, 2024 - nature.com
Sleep-disordered breathing (SDB) is a prevalent disorder characterized by recurrent
episodic upper airway obstruction. Using data from the Hispanic Community Health …

Metabolomics in sleep, insomnia and sleep apnea

E Humer, C Pieh, G Brandmayr - International journal of molecular …, 2020 - mdpi.com
Sleep-wake disorders are highly prevalent disorders, which can lead to negative effects on
cognitive, emotional and interpersonal functioning, and can cause maladaptive metabolic …

[HTML][HTML] Plasma profiling reveals a blood-based metabolic fingerprint of obstructive sleep apnea

L Pinilla, ID Benítez, F Santamaria-Martos… - Biomedicine & …, 2022 - Elsevier
Introduction Obstructive sleep apnea (OSA) is a chronic, heterogeneous and
multicomponent disorder with associated cardiovascular and metabolic alterations. Despite …

Emerging role of metabolomics for biomarker discovery in obstructive sleep apnea

Mohit, MS Tomar, D Sharma, S Nandan, A Pateriya… - Sleep and …, 2023 - Springer
Obstructive sleep apnea (OSA) is characterized by the complete or partial blockage of the
upper airway passage during sleep which causes repetitive breaks in sleep and may result …

[HTML][HTML] Surface active salivary metabolites indicate oxidative stress and inflammation in obstructive sleep apnea

J Kim, S An, Y Kim, DW Yoon, SA Son… - Allergy, Asthma & …, 2023 - ncbi.nlm.nih.gov
Purpose Obstructive sleep apnea (OSA), a highly prevalent and potentially serious sleep
disorder, requires effective screening tools. Saliva is a useful biological fluid with various …

Transcription Factor McHB7 Improves Ice Plant Drought Tolerance through ABA Signaling Pathway

X Zhang, Z Cheng, G Fan, D Zhu, B Tan… - International Journal of …, 2024 - mdpi.com
As global climate change continues, drought episodes have become increasingly frequent.
Studying plant stress tolerance is urgently needed to ensure food security. The common ice …

Metabolism of sleep and aging: Bridging the gap using metabolomics

A Sengupta, AM Weljie - Nutrition and Healthy Aging, 2019 - content.iospress.com
Sleep is a conserved behavior across the evolutionary timescale. Almost all known animal
species demonstrate sleep or sleep like states. Despite extensive study, the mechanistic …