Autoantibody specificities in myasthenia gravis; implications for improved diagnostics and therapeutics

K Lazaridis, SJ Tzartos - Frontiers in immunology, 2020 - frontiersin.org
Myasthenia gravis (MG) is an autoimmune disease characterized by muscle weakness and
fatiguability of skeletal muscles. It is an antibody-mediated disease, caused by …

Myasthenia gravis: pathogenic effects of autoantibodies on neuromuscular architecture

I Koneczny, R Herbst - Cells, 2019 - mdpi.com
Myasthenia gravis (MG) is an autoimmune disease of the neuromuscular junction (NMJ).
Autoantibodies target key molecules at the NMJ, such as the nicotinic acetylcholine receptor …

Unveiling the proteome-wide autoreactome enables enhanced evaluation of emerging CAR T cell therapies in autoimmunity

A Bodansky, JL David, A Rallistan, M Kalaycioglu… - The Journal of clinical …, 2024 - jci.org
Given the global surge in autoimmune diseases, it is critical to evaluate emerging
therapeutic interventions. Despite numerous new targeted immunomodulatory therapies …

[图书][B] Muscle biopsy: a practical approach: expert consult; online and print

V Dubowitz, CA Sewry, A Oldfors - 2013 - books.google.com
2014 BMA Medical Book Awards Highly Commended in Pathology category! Muscle Biopsy:
A Practical Approach gives you all of the unparalleled guidance necessary to effectively …

Myasthenia gravis: autoantibody specificities and their role in MG management

K Lazaridis, SJ Tzartos - Frontiers in neurology, 2020 - frontiersin.org
Myasthenia gravis (MG) is the most common autoimmune disorder affecting the
neuromuscular junction, characterized by skeletal muscle weakness and fatigability. It is …

Management of juvenile myasthenia gravis

K O'Connell, S Ramdas, J Palace - Frontiers in Neurology, 2020 - frontiersin.org
Juvenile Myasthenia Gravis (JMG) is a rare disorder, defined as myasthenia gravis in
children younger than 18 years of age. While clinical phenotypes are similar to adults, there …

Diagnosis of myasthenia gravis

RT Rousseff - Journal of clinical medicine, 2021 - mdpi.com
The diagnosis of autoimmune Myasthenia Gravis (MG) remains clinical and rests on the
history and physical findings of fatigable, fluctuating muscle weakness in a specific …

Myasthenia gravis: from autoantibodies to therapy

R Mantegazza, P Bernasconi… - Current Opinion in …, 2018 - journals.lww.com
Myasthenia gravis: from autoantibodies to therapy : Current Opinion in Neurology
Myasthenia gravis: from autoantibodies to therapy : Current Opinion in Neurology Log in or …

Agonist antibody to MuSK protects mice from MuSK myasthenia gravis

J Oury, B Gamallo-Lana, L Santana, C Steyaert… - Proceedings of the …, 2024 - pnas.org
Myasthenia gravis (MG) is a chronic and severe disease of the skeletal neuromuscular
junction (NMJ) in which the effects of neurotransmitters are attenuated, leading to muscle …

Complement inhibitor therapy for myasthenia gravis

K Albazli, HJ Kaminski, JF Howard Jr - Frontiers in Immunology, 2020 - frontiersin.org
Complement activation as a driver of pathology in myasthenia gravis (MG) has been
appreciated for decades. The terminal complement component [membrane attack complex …