DNA repair mechanisms allow maintain genomic stability and proper functioning within the
cells. Any aberrations may cause an increased risk of many diseases such as cancer. The …

Increasing trend in oral cancer (0.6% per year) and its related mortality has been reported
worldwide since the past decade. The United States alone reports an increase of 57% within …

Single nucleotide polymorphisms of DNA repair genes alter protein function and modulate
DNA repair efficiency in various cancers. The X-ray repair cross-complementing group …

Background: Accumulated evidence shows that DNA repair gene X-ray repair cross
complementing group 1 (XRCC1) may determine individual susceptibility to head and neck …

Purpose To evaluate the prognostic significance of DNA excision repair gene
polymorphisms, excision repair cross-complementation group 1 (ERCC1) and X-ray repair …

Head and neck cancer (HNC) is one of the most common malignancies in the world. HNC is
a group of cancers that starts in the mouth, nose, throat, larynx, sinuses, or salivary glands …

Background The X‐ray repair cross complementing group 1 (XRCC1) is a DNA repair gene.
Various studies have examined the association between XRCC1 Arg194Trp polymorphism …

Background and purpose: Oral squamous cell carcinoma (OSCC) is the most common tumor
of the head and neck. XRCC1 is a DNA repair gene and there are controversies about the …

This study aimed to explore gene expression profiles that drive malignancy from low-to high-
grade head and neck carcinomas (HNC), as well as to analyze their correlations with …

Amaç: XRCC1 geni, serbest oksijen radikallerinin, iyonize radyasyonun, ultraviyole ve
alkilleyici mutajenlerin yaptığı baz değişimi sonucu oluşan baz kesip çıkarma (eksizyon) …