Abstract α-Amino nitrile compounds have a profound impact on bio-chemical sciences, as
they have been prepared from inexpensive starting materials and have become valuable …

Due to their numerous reactivity modes, α‐aminonitriles represent versatile and valuable
building blocks in organic total synthesis. Since their discovery by Adolph Strecker in 1850 …

Secondary piperidines are ideal pharmaceutical building blocks owing to the prevalence of
piperidines in commercial drugs. Here, we report an electrochemical method for cyanation of …

A new methodology to afford α-amino nitriles through oxidative cyanomethylation of amines
using nitromethane as the methylene source in the presence of Me3SiCN without the …

This review is based on the analysis of recent developments on cyanation reactions for the
synthesis of nitriles (RCN) through transition metal mediated cyanation reaction as well as …

The Strecker reaction is the most widely applied three-component reaction. Although highly
useful for the preparation of α-amino nitriles, α-amino acids, hydantoins and numerous …

A facile, one-pot, and proficient method was developed for the production of various 2-
arylaminobenzimidazoles. This methodology is based for the first time on a copper catalyst …

The copper (II)-promoted free-radical oxidative difunctionalization of terminal alkenes to
access ketoazides by utilizing molecular oxygen has been reported. A series of styrene …

Strecker reaction is widely applied for the synthesis of amino acids from aldehydes, amines
and cyanides. Herein, we report the FeI 2-catalyzed reductive Strecker type reaction of …

We have developed a Michael-addition/cyclization procedure between ene–yne–ketones
and TMSCN under metal-free conditions. A wide range of cyanofurans was delivered in high …