Although 5-fluorouracil (5-FU)-based chemotherapy is the major treatment for colorectal
cancer, it has disadvantages such as systemic toxicity, lack of effectiveness and selectivity …

Mammalian carboxylesterases (CEs) are key enzymes from the serine hydrolase
superfamily. In the human body, two predominant carboxylesterases (CES1 and CES2) …

Knowledge of bacterial lipolytic enzymes is increasing at a rapid and exciting rate. To obtain
an overview of this industrially very important class of enzymes and their characteristics, we …

Abstract Esterases (EC 3.1. 1. x) represent a diverse group of hydrolases catalyzing the
cleavage and formation of ester bonds and are widely distributed in animals, plants and …

▪ Abstract Bacteria produce and secrete lipases, which can catalyze both the hydrolysis and
the synthesis of long-chain acylglycerols. These reactions usually proceed with high …

The α/β hydrolase fold is a typical example of a tertiary fold adopted by proteins that have no
obvious sequence similarity, but nevertheless, in the course of evolution, diverged from a …

From reviews to the first edtion:" Bornscheuer and Kazlauskas have set out, and succeeded,
in producing a definitive manual on hydrolytic enzymes (especially lipases, esterases, and …

The Arabidopsis EDS1 and PAD4 genes encode lipase‐like proteins that function in
resistance (R) gene‐mediated and basal plant disease resistance. Phenotypic analysis of …

A general strategy is described for designing proteins that self assemble into large
symmetrical nanomaterials, including molecular cages, filaments, layers, and porous …

Esterases and lipases both hydrolyse ester bonds. Whereas the lipases display high activity
towards the aggregated state of its substrate, the esterases typically show highest activity …