The ways in which acyclic chains are synthesized may often be classified into one of four strategies (Scheme 1). The classical one directional Linear Synthesis and Convergent …
Well over a decade ago, two reviews were contributed to the Organic Reactions series covering substitution and conjugate addition reactions in organocopper chemistry. Their …
AB Smith, DS Kim - The Journal of Organic Chemistry, 2006 - ACS Publications
N-Toluenesulfonyl aziridines comprise effective second electrophiles in the solvent controlled three-component linchpin union of silyl dithianes for the stereocontrolled …
CJ Easton, CMM Hughes, GP Savage… - Advances in Heterocyclic …, 1994 - Elsevier
Publisher Summary This chapter reviews the cycloaddition reactions of nitrile oxides with alkenes. It covers the literature published between 1985 and 1992. The chapter emphasizes …
We describe a general procedure for the synthesis of miktoarm star triblock copolymers with a hydrocarbon, a fluoropolymer, and a hydrophilic segment. Several μ-(polyethylethylene) …
V Jäger, D Schröter, B Koppenhoefer - Tetrahedron, 1991 - Elsevier
The asymmetric Sharpless epoxidation of divinylcarbinol (1), a secondary, achiral allylic alcohol, is described in detail. The epoxidation proceeds with high enantio-control and …
JG Martynow, J Jóźwik, W Szelejewski, O Achmatowicz… - 2007 - Wiley Online Library
This paper describes a new synthesis of latanoprost (1) that afforded high purity latanoprost in 16.9% overall yield in eight synthetic steps from sulfone 4. The “α chain” in a derivative of …
B Zhou, Y Li - Tetrahedron Letters, 2012 - Elsevier
A synthesis of Entecavir (BMS-200475) was achieved starting from 1, 3-propanediol in 15 steps and 23.4% overall yield. A unique feature of the synthetic route is that the five …
Abstract Bimatoprost (1) and Latanoprost (2) are prostaglandin analogues widely used for glaucoma treatment. We have developed a new chemoenzymatic synthesis for 1 and 2 …