The epithelial–mesenchymal transition (EMT) is an essential event during cell development,
in which epithelial cells acquire mesenchymal fibroblast-like features including reduced …

Among all cells, fibroblasts could be considered the cockroaches of the human body. They
survive severe stress that is usually lethal to all other cells, and they are the only normal cell …

Ovarian fibrosis is a pathological condition associated with aging and is responsible for a
variety of ovarian dysfunctions. Given the known contributions of tissue fibrosis to …

(Myo) fibroblasts are key players for maintaining skin homeostasis and for orchestrating
physiological tissue repair.(Myo) fibroblasts are embedded in a sophisticated extracellular …

Simple Summary FAPI represents a novel class of radiotracers demonstrating promising
results in terms of a high uptake in concordance with low background noise in several …

Tissue stiffening is a hallmark of fibrotic disorders but has traditionally been regarded as an
outcome of fibrosis, not a contributing factor to pathogenesis. In this study, we show that …

The crucial role played by the myofibroblast in wound healing and pathological organ
remodeling is well established; the general mechanisms of extracellular matrix synthesis …

It is generally accepted that fibroblast-to-myofibroblast differentiation represents a key event
during wound healing and tissue repair. The high contractile force generated by …

Macrophages perform both injury-inducing and repair-promoting tasks in different models of
inflammation, leading to a model of macrophage function in which distinct patterns of …

Acute inflammation is a recognised part of normal wound healing. However, when
inflammation fails to resolve and a chronic inflammatory response is established this …