The claustrum has been linked to attention and sleep. We hypothesized that this reflects a
shared function, determining responsiveness to stimuli, which spans the axis of …

The synthetic opioid fentanyl is a major contributor to the current opioid addiction crisis. We
report that claustral neurons projecting to the frontal cortex limit oral fentanyl self …

The Claustrum/dorsal endopiriform cortex complex (CLA) is an enigmatic brain region with
extensive glutamatergic projections to multiple cortical areas. The transcription factor Nurr1 …

Cortical activity is constantly fluctuating between distinct spatiotemporal activity patterns
denoted by changes in brain state. States of cortical desynchronization arise during motor …

Neural activity in the claustrum has been associated with a range of vigilance states, yet the
activity patterns and efficacy of synaptic communication of identified claustrum neurons have …

Recent evidence indicates that neuronal activity within the claustrum (CLA) may be central
to cellular and behavioral responses to psychedelic hallucinogens. The CLA prominently …

The claustrum is a small subcortical structure with widespread connections to disparate
regions of the cortex. However, the impact of the claustrum on cortical activity is not fully …

Slow waves are a distinguishing feature of non-rapid-eye-movement (NREM) sleep, an
evolutionarily conserved process critical for brain function. Non-human studies suggest that …

The cerebral cortex generates flexible behavior by learning. Reinforcement learning is
thought to be driven by error signals in midbrain dopamine neurons. However, they project …

Despite substantial neuroscience research in the last decade revealing the claustrum's
prominent role in mammalian forebrain organization, as evidenced by its extraordinarily …