This review focuses on cytotoxic rhenium compounds in terms of IC 50 values, their mode of
action in biological systems and their status in clinical trials. Biological studies of different …

Very rich coordination chemistry of thiosemicarbazide based ligands is mainly associated
with the diversity of their Schiff base derivatives, known as thiosemicarbazones. The …

High-valent oxo-rhenium (V)(oxo-Re (V)) complexes are emerging as potential alternatives
to platinum (Pt)-based chemotherapeutics. While potent in vitro antitumor activity, novel …

This paper reports the synthesis and structural characterization of novel mixed ligand-metal
complexes derived from 4-((2-(phenylcarbamothioyl) hydrazinylidene) methyl) benzoic acid …

Chemotherapy with the cytotoxic platinum (Pt) drugs cisplatin, carboplatin, and oxaliplatin is
the mainstay of anticancer therapy in the clinic. The antitumor activity of Pt drugs originates …

Cyclometallated palladium (II) and platinum (II) pyrenyl-derived thiosemicarbazone (H2PrR)
complexes of the type [M4 (μ-S-PrR-κ3-C, N, S) 4](M= PdII, PtII; R= ethyl, cyclohexyl) have …

Tridentate thiosemicarbazone ligands with an ONS donor set, H 2 LR (R= Me and Et) were
prepared by reactions of 1-phenyl-1, 3-butanedione with 4-R-3-thiosemicarbazides. H 2 LR …

Stable organogold (III) compounds of the composition [AuIII (Hdamp)(L1)] Cl are formed from
reactions of [AuCl2 (damp)] with H2L1 (damp−= dimethylaminomethylphenyl; H2L1= N …

Background Heterometallic gold metallacages are of great interest for the incorporation of
several cations. Especially in nuclear medicine, those metallacages can serve as a platform …

Ruthenium complexes have been assessed as anti-tumor agents against cancer cells. In
this project, new heteroleptic ruthenium (II) complexes with general formulae [Ru …