Bioactive properties of the aromatic molecules of spearmint (Mentha spicata L.) essential oil: A review

LL Zhang, Y Chen, ZJ Li, X Li, G Fan - Food & Function, 2022 - pubs.rsc.org
Spearmint belongs to the genus Mentha in the family Labiatae (Lamiaceae), which is
cultivated worldwide for its remarkable aroma and commercial value. The aromatic …

Essential oils as a potential neuroprotective remedy for age-related neurodegenerative diseases: A review

A Abd Rashed, AZ Abd Rahman, DNG Rathi - Molecules, 2021 - mdpi.com
Despite the improvements in life expectancy, neurodegenerative conditions have arguably
become the most dreaded maladies of older people. The neuroprotective and anti-ageing …

Contribution of chemical permeation enhancers to the process of transdermal drug delivery: Adsorption, microscopic interactions, and mechanism

Z Jiang, S Liu, H Zhang, Y Li, S Yuan - Colloids and Surfaces B …, 2024 - Elsevier
Transdermal drug delivery (TDD) has attracted widespread attention because of the
advantage of its non-invasive nature, easy self-administration, and low side effects. The key …

Inhibition of GPR17 with cangrelor improves cognitive impairment and synaptic deficits induced by Aβ1–42 through Nrf2/HO-1 and NF-κB signaling pathway in mice

SY Jin, X Wang, XT Xiang, YM Wu, J Hu, YY Li… - International …, 2021 - Elsevier
The accumulation of amyloid beta (Aβ) in the brain is thought to be associated with cognitive
deficits in Alzheimer's disease (AD). However, current methods to combat Aβ neurotoxicity …

(-)-Carveol prevents gastric ulcers via cytoprotective, antioxidant, antisecretory and immunoregulatory mechanisms in animal models

CAL Serafim, MEC Araruna, EB Alves Júnior… - Frontiers in …, 2021 - frontiersin.org
Background:(-)-Carveol (p-Mentha-6, 8-dien-2-ol) is a monocyclic monoterpenic alcohol,
present in essential oils of plant species such as Cymbopogon giganteus, Illicium …

Multiunit in vitro colon model for the evaluation of prebiotic potential of a fiber plus D-limonene food supplement

L Nissen, MC Valerii, E Spisni, F Casciano, A Gianotti - Foods, 2021 - mdpi.com
The search for new fiber supplements that can claim to be “prebiotic” is expanding fast, as
the role of prebiotics and intestinal microbiota in well-being has been well established. This …

Mechanistic aspects of Apiaceae family spices in ameliorating Alzheimer's disease

N Sharma, MA Tan, SSA An - Antioxidants, 2021 - mdpi.com
Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases
worldwide. In an effort to search for new strategies for treating AD, natural products have …

[Retracted] Carveol Promotes Nrf2 Contribution in Depressive Disorders through an Anti‐inflammatory Mechanism

AJ Muhammad, L Hao, LT Al Kury… - Oxidative Medicine …, 2022 - Wiley Online Library
Major depressive disorder (MDD) is a progressive deteriorating mental state with a feeling of
worthlessness and frequent mood swings. Several studies reported the favorable effects of …

Cotinine and 6-Hydroxy-L-Nicotine Reverses Memory Deficits and Reduces Oxidative Stress in Aβ25-35-Induced Rat Model of Alzheimer's Disease

RS Boiangiu, M Mihasan, DL Gorgan, BA Stache… - Antioxidants, 2020 - mdpi.com
The nicotinic derivatives, cotinine (COT), and 6-hydroxy-L-nicotine (6HLN), showed
promising cognitive-improving effects without exhibiting the nicotine's side-effects. Here, we …

Carveol mitigates the development of the morphine anti-nociceptive tolerance, physical dependence, and conditioned place preference in mice

I Badshah, NG Qazi, M Anwar, B Shaukat, MI Khan… - Heliyon, 2024 - cell.com
Emergence of analgesic tolerance and dependence to morphine is frequently the limiting
factor in the use of this agent in the management of pain. Hence, this study aimed to …