The participation of astrocytes in brain computation was hypothesized in 1992, coinciding
with the discovery that these cells display a form of intracellular Ca2+ signaling sensitive to …

Blood vessels are critical to deliver oxygen and nutrients to tissues and organs throughout
the body. The blood vessels that vascularize the central nervous system (CNS) possess …

Astrocytes play crucial roles in regulating brain circuit formation and physiology. Recent
technological advances have revealed unprecedented levels of astrocyte diversity …

The astrocyte, a major glial cell type in the central nervous system (CNS), is widely regarded
as a functionally diverse mediator of homeostasis. During development and throughout …

Windows of plasticity allow environmental experiences to produce intense activity-
dependent changes during postnatal development. The reordering and refinement of neural …

Neuroinflammation is a hallmark of ischemic stroke, which is a leading cause of death and
long‐term disability. Understanding the exact cellular signaling pathways that initiate and …

Ischemic stroke is a leading cause of morbidity and mortality and disproportionally affects
women, in part due to their higher longevity. Older women have poorer outcomes after …

Astrocytes are intimately linked with brain blood vessels, an essential relationship for
neuronal function. However, astroglial factors driving these physical and functional …

In the brain, astrocytes regulate shape and functions of the synaptic and vascular
compartments through a variety of released factors and membrane-bound proteins. An …

Experimental autoimmune encephalomyelitis (EAE) can be induced in many animal strains
by inoculation with central nervous system antigens and adjuvant or by the passive transfer …