The impact of substance abuse on HIV-mediated neuropathogenesis in the current ART era
V Chilunda, TM Calderon, P Martinez-Aguado… - Brain research, 2019 - Elsevier
Approximately 37 million people worldwide are infected with human immunodeficiency virus
(HIV). One highly significant complication of HIV infection is the development of HIV …
(HIV). One highly significant complication of HIV infection is the development of HIV …
[HTML][HTML] Transcriptional profiling of CD11c-positive microglia accumulating around amyloid plaques in a mouse model for Alzheimer's disease
W Kamphuis, L Kooijman, S Schetters, M Orre… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Amyloid plaques in Alzheimer's disease (AD) mice are surrounded by activated microglia.
The functional role of microglia activation in AD is not well understood; both detrimental and …
The functional role of microglia activation in AD is not well understood; both detrimental and …
Endogenous opiates and behavior: 2015
RJ Bodnar - Peptides, 2017 - Elsevier
This paper is the thirty-eighth consecutive installment of the annual review of research
concerning the endogenous opioid system. It summarizes papers published during 2015 …
concerning the endogenous opioid system. It summarizes papers published during 2015 …
HIV-1 is transported into the central nervous system by trafficking infected cells
LP Kincer, G Schnell, R Swanstrom… - Pathogens and …, 2023 - pmc.ncbi.nlm.nih.gov
Background: In this work, we carried out a cross-sectional study examining HIV-1 and HCV
free virus concentrations in blood and cerebrospinal fluid (CSF) to determine whether HIV-1 …
free virus concentrations in blood and cerebrospinal fluid (CSF) to determine whether HIV-1 …
Central HIV-1 Tat exposure elevates anxiety and fear conditioned responses of male mice concurrent with altered mu-opioid receptor-mediated G-protein activation …
Co-exposure to opiates and HIV/HIV proteins results in enhanced CNS morphological and
behavioral deficits in HIV+ individuals and in animal models. Opiates with abuse liability …
behavioral deficits in HIV+ individuals and in animal models. Opiates with abuse liability …
An infectious murine model for studying the systemic effects of opioids on early HIV pathogenesis in the gut
Opioids are known to exacerbate HIV pathogenesis, however current studies have been
limited by models of HIV infection. Given that HIV causes many systemic effects via direct …
limited by models of HIV infection. Given that HIV causes many systemic effects via direct …
[PDF][PDF] Blood-brain barrier and neuro-AIDS.
YL Zhang, YB Ouyang, LG Liu… - European Review for …, 2015 - europeanreview.org
Neuro-AIDS is becoming a major health problem among AIDS patients who experience
improved survival under combined antiretroviral therapy (cART). Neuronal injury and loss …
improved survival under combined antiretroviral therapy (cART). Neuronal injury and loss …
Opioid-mediated HIV-1 immunopathogenesis
Despite the ability of combination antiretroviral therapy to dramatically suppress viremia, the
brain continues to be a reservoir of HIV-1 low-level replication. Adding further complexity to …
brain continues to be a reservoir of HIV-1 low-level replication. Adding further complexity to …
Follicular dendritic cells of lymph nodes as human immunodeficiency virus/simian immunodeficiency virus reservoirs and insights on cervical lymph node
A hallmark feature of follicular dendritic cells (FDCs) within the lymph nodes (LNs) is their
ability to retain antigens and virions for a prolonged duration. FDCs in the cervical lymph …
ability to retain antigens and virions for a prolonged duration. FDCs in the cervical lymph …