Ferrocene-containing hybrids as potential anticancer agents: Current developments, mechanisms of action and structure-activity relationships

R Wang, H Chen, W Yan, M Zheng, T Zhang… - European Journal of …, 2020 - Elsevier
Cancer is one of the most fatal threatens to human health throughout the world. The major
challenges in the control and eradication of cancers are the continuous emergency of drug …

Organometallic–peptide bioconjugates: synthetic strategies and medicinal applications

B Albada, N Metzler-Nolte - Chemical reviews, 2016 - ACS Publications
Peptides are important biological molecular entities in biomedical research. They can be
prepared in a large variety of shapes, with a host of chemical functions, and tailored for …

Small cationic antimicrobial peptides delocalize peripheral membrane proteins

M Wenzel, AI Chiriac, A Otto… - Proceedings of the …, 2014 - National Acad Sciences
Short antimicrobial peptides rich in arginine (R) and tryptophan (W) interact with
membranes. To learn how this interaction leads to bacterial death, we characterized the …

Allicin induces thiol stress in bacteria through S-allylmercapto modification of protein cysteines

A Müller, J Eller, F Albrecht, P Prochnow… - Journal of Biological …, 2016 - ASBMB
Allicin (diallyl thiosulfinate) from garlic is a highly potent natural antimicrobial substance. It
inhibits growth of a variety of microorganisms, among them antibiotic-resistant strains …

Recent advances in the design of antimicrobial peptide conjugates

ARP Silva, MS Guimarães, J Rabelo… - Journal of Materials …, 2022 - pubs.rsc.org
Antimicrobial peptides (AMPs) are ubiquitous host defense peptides characterized by their
antibiotic activity and lower propensity for developing resistance compared to classic …

Highly potent antibacterial organometallic peptide conjugates

B Albada, N Metzler-Nolte - Accounts of chemical research, 2017 - ACS Publications
Conspectus Resistance of pathogenic bacteria against currently marketed antibiotics is
again increasing. To meet the societal need for effective cures, scientists are faced with the …

Insights into biofouling in reverse osmosis membrane: A comprehensive review on techniques for biofouling assay

D Suresh, PS Goh, AF Ismail, TW Wong - Journal of Environmental …, 2023 - Elsevier
Biofouling is a critical concern in reverse osmosis as it significantly deteriorates the efficacy
of the treatment processes. A biofouling assessment technique offers an insight into the …

Analysis of the mechanism of action of potent antibacterial hetero-tri-organometallic compounds: a structurally new class of antibiotics

M Wenzel, M Patra, CHR Senges, I Ott… - ACS chemical …, 2013 - ACS Publications
Two hetero-tri-organometallic compounds with potent activity against Gram-positive bacteria
including multi-resistant Staphylococcus aureus (MRSA) were identified. The compounds …

Tryptophan, more than just an interfacial amino acid in the membrane activity of cationic cell-penetrating and antimicrobial peptides

S Khemaissa, A Walrant, S Sagan - Quarterly Reviews of Biophysics, 2022 - cambridge.org
Trp is unique among the amino acids since it is involved in many different types of
noncovalent interactions such as electrostatic and hydrophobic ones, but also in π-π, π …

Bio‐Organometallic Derivatives of Antibacterial Drugs

MA Sierra, L Casarrubios… - Chemistry–A European …, 2019 - Wiley Online Library
Overuse and misuse of antibacterial drugs has resulted in bacteria resistance and in an
increase in mortality rates due to bacterial infections. Therefore, there is an imperative …