Scanning ion conductance microscopy

C Zhu, K Huang, NP Siepser, LA Baker - Chemical Reviews, 2020 - ACS Publications
Scanning ion conductance microscopy (SICM) has emerged as a versatile tool for studies of
interfaces in biology and materials science with notable utility in biophysical and …

Multifunctional scanning ion conductance microscopy

A Page, D Perry, PR Unwin - Proceedings of the …, 2017 - royalsocietypublishing.org
Scanning ion conductance microscopy (SICM) is a nanopipette-based technique that has
traditionally been used to image topography or to deliver species to an interface, particularly …

Downstream processability of crystal habit-modified active pharmaceutical ingredient

N Pudasaini, PP Upadhyay, CR Parker… - … process research & …, 2017 - ACS Publications
Efficient downstream processing of active pharmaceutical ingredients (APIs) can depend
strongly on their particulate properties, such as size and shape distributions. Especially in …

Different Dissolution Molecular Pathways of Azilsartan Crystals with Different Forms Revealed by In Situ Atomic Force Microscopy

S Song, L Wang, G Xie, Y Qu, H Li… - The Journal of …, 2023 - ACS Publications
Here, using in situ atomic force microscopy (AFM), the dissolution behaviors and dissolution
molecular pathways of two azilsartan crystals, the isopropanol solvate (AZ-IPA), and form I …

Electrochemistry and optical microscopy

F Kanoufi - arXiv preprint arXiv:2109.12322, 2021 - arxiv.org
Electrochemistry exploits local current heterogeneities at various scales ranging from the
micrometer to the nanometer. The last decade has witnessed unprecedented progress in the …

Application of UV dissolution imaging to pharmaceutical systems

B Brown, A Ward, Z Fazili, J Østergaard… - Advanced Drug Delivery …, 2021 - Elsevier
UV–vis spectrometry is widely used in the pharmaceutical sciences for compound
quantification, alone or in conjunction with separation techniques, due to most drug entities …

Multiphase assembly of small molecule microcrystalline peptide hydrogel allows immunomodulatory combination therapy for long‐term heart transplant survival

P Majumder, Y Zhang, M Iglesias, L Fan, JA Kelley… - Small, 2020 - Wiley Online Library
Combination therapies that target multiple pathways involved in immune rejection of
transplants hold promise for patients in need of restorative surgery. Herein, a noninteracting …

Characterization of Mass Transfer within the Crystal-Solution Boundary Layer of l-Alanine {120} Faces Using Laser Interferometry during Growth and Dissolution

ST Nicholson, KJ Roberts, T Izumi… - Crystal Growth & Design, 2023 - ACS Publications
Crystallization and dissolution are important processes to consider in drug development as
well as many other industrial processes. Many current growth and dissolution models are …

Dissolution of indomethacin crystals into a polymer melt: role of diffusion and fragmentation

DE Moseson, AS Parker, CJ Gilpin… - Crystal Growth & …, 2019 - ACS Publications
The dissolution or melting of a crystalline drug into a molten polymeric matrix underpins the
fabrication of a number of drug delivery systems. However, little is known about how crystals …

Modeling Morphologies of Organic Crystals via Kinetic Monte Carlo Simulations: Noncentrosymmetric Growth Units

T Mazal, MF Doherty - Crystal Growth & Design, 2024 - ACS Publications
Crystal morphologies are governed by growth conditions, such as supersaturation and
temperature, as well as by the bonding structures of growth units within the crystal lattice …