HIV-associated lung disease

I Konstantinidis, K Crothers, KM Kunisaki… - Nature Reviews …, 2023 - nature.com
Lung disease encompasses acute, infectious processes and chronic, non-infectious
processes such as chronic obstructive pulmonary disease, asthma and lung cancer. People …

[HTML][HTML] Ferroptosis in viral infection: the unexplored possibility

M Wang, B Joshua, N Jin, S Du, C Li - Acta Pharmacologica Sinica, 2022 - nature.com
Virus-induced cell death has long been thought of as a double-edged sword in the inhibition
or exacerbation of viral infections. The vital role of iron, an essential element for various …

[HTML][HTML] Glutathione supplementation as an adjunctive therapy in COVID-19

V Guloyan, B Oganesian, N Baghdasaryan, C Yeh… - Antioxidants, 2020 - mdpi.com
Morbidity and mortality of coronavirus disease 2019 (COVID-19) are due in large part to
severe cytokine storm and hypercoagulable state brought on by dysregulated host …

Glutathione: Role in oxidative/nitrosative stress, antioxidant defense, and treatments

S Raj Rai, C Bhattacharyya, A Sarkar… - …, 2021 - Wiley Online Library
Glutathione (GSH) is the most abundant cellular tripeptide (L‐γ‐glutamate‐L‐cysteinyl‐
glycine) which is as critical as oxygen and water. This low molecular mass antioxidant has a …

Application of glutathione as anti-oxidative and anti-aging drugs

T Homma, J Fujii - Current drug metabolism, 2015 - ingentaconnect.com
Glutathione (GSH), an abundant tripeptidyl molecule, plays pivotal roles in protecting cells
against oxidative stress-induced cellular damage and in detoxifying xenobiotics and drug …

Glutathione and infection

D Morris, M Khurasany, T Nguyen, J Kim… - … et Biophysica Acta (BBA …, 2013 - Elsevier
BACKGROUND: The tripeptide γ-glutamylcysteinylglycine or glutathione (GSH) has
demonstrated protective abilities against the detrimental effects of oxidative stress within the …

[HTML][HTML] Mechanisms of Control of Mycobacterium tuberculosis by NK Cells: Role of Glutathione

M Allen, C Bailey, I Cahatol, L Dodge, J Yim… - Frontiers in …, 2015 - frontiersin.org
Tuberculosis (TB), caused by Mycobacterium tuberculosis (M. tb), continues to be one of the
most prevalent infectious diseases in the world. There is an upward trend in occurrence due …

Randomized controlled trial of oral glutathione supplementation on body stores of glutathione

JP Richie, S Nichenametla, W Neidig… - European journal of …, 2015 - Springer
Purpose Glutathione (GSH), the most abundant endogenous antioxidant, is a critical
regulator of oxidative stress and immune function. While oral GSH has been shown to be …

[HTML][HTML] Glucose metabolism in T cells and monocytes: new perspectives in HIV pathogenesis

CS Palmer, CL Cherry, I Sada-Ovalle, A Singh… - …, 2016 - thelancet.com
Activation of the immune system occurs in response to the recognition of foreign antigens
and receipt of optimal stimulatory signals by immune cells, a process that requires energy …

The interplay between systemic inflammation, oxidative stress, and tissue remodeling in tuberculosis

EP Amaral, CL Vinhaes… - Antioxidants & redox …, 2021 - liebertpub.com
Significance: Excessive and prolonged proinflammatory responses are associated with
oxidative stress, which is commonly observed during chronic tuberculosis (TB). Such …