Ulcerative colitis and Crohn's disease are the principal forms of inflammatory bowel disease.
Both represent chronic inflammation of the gastrointestinal tract, which displays …

OBJECTIVES: In 2015, the Selecting Therapeutic Targets in Inflammatory Bowel Disease
(STRIDE) program proposed shifting the therapeutic focus on ulcerative colitis (UC) toward …

Background The Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE)
initiative of the International Organization for the Study of Inflammatory Bowel Diseases …

Background: The contemporary management of ambulatory ulcerative colitis (UC) continues
to be challenging with∼ 20% of children needing a colectomy within childhood years. We …

There are several scoring systems presently available to classify disease severity in
ulcerative colitis [UC] within the multiple domains of disease activity, which aid objective …

Background Endoscopic assessment of mucosal disease activity is routinely used to
determine eligibility and response to therapy in clinical trials of ulcerative colitis. The …

Increased knowledge of the intricate pathogenesis of ulcerative colitis has triggered an
advance in drug development during the past two decades, resulting in the advent of several …

Pediatric-onset colitis and inflammatory bowel disease (IBD) have significant effects on the
growth of infants and children, but the etiopathogenesis underlying disease subtypes …

Background Immune-mediated diarrhea and colitis (IMDC) can limit immune checkpoint
inhibitors (ICIs) treatment, which is efficacious for advanced malignancies. Steroids and …

Primary sclerosing cholangitis (PSC) is an immune-mediated disease of the bile ducts that
co-occurs with inflammatory bowel disease (IBD) in almost 90% of cases. Colorectal cancer …