Malaria is still a major public health problem in Brazil, with approximately 306 000 registered
cases in 2009, but it is estimated that in the early 1940s, around six million cases of malaria …

Plasmodium vivax is the second most prevalent cause of malaria worldwide and the leading
cause of malaria outside of Africa. Although infections are seldom fatal clinical disease can …

Plasmodium vivax infection, the predominant cause of malaria in Asia and Latin America,
affects~ 14 million individuals annually, with considerable adverse effects on wellbeing and …

BACKGROUND. Plasmodium vivax is the most widespread human malaria geographically;
however, no effective vaccine exists. Red blood cell invasion by the P. vivax merozoite …

Plasmodium vivax Duffy Binding Protein (PvDBP) is the most promising vaccine candidate
for P. vivax malaria. The polymorphic nature of PvDBP induces strain-specific immune …

Population studies show that individuals acquire immunity to Plasmodium vivax more
quickly than Plasmodium falciparum irrespective of overall transmission intensity, resulting …

Abstract The Plasmodium vivax Duffy-binding protein (DBP) is a prime target of the
protective immune response and a promising vaccine candidate for P. vivax malaria …

In this work, we developed a computational protocol that employs multiple molecular
docking experiments, followed by pose clustering, molecular dynamic simulations (10 ns) …

A single exposure to many viral and bacterial pathogens typically induces life-long immunity,
however, the development of the protective immunity to Plasmodium parasites is strikingly …

Malaria caused by Plasmodium vivax continues being one of the most important infectious
diseases around the world; P. vivax is the second most prevalent species and has the …